Today, the production and use of various samples of recombinant protein/polypeptide toxins
is known and is actively develo**. This review presents state-of-the-art in research and …

The term “prion disease” encompasses a group of neurodegenerative diseases affecting
both humans and animals. Currently, there is no effective therapy and all forms of prion …

Chronic wasting disease (CWD) is a prion disease affecting deer, elk and moose in North
America and reindeer, moose and red deer in Northern Europe. Pathogenesis is driven by …

Prion protein has two isoforms including cellular prion protein (PrPC) and scrapie prion
protein (PrPSc). PrPSc is the pathological aggregated form of prion protein and it plays an …

Chronic wasting disease (CWD) is a prion disease of free‐ranging and farmed cervids that is
highly contagious because of extensive prion shedding and prion persistence in the …

Prion diseases are a group of fatal neurodegenerative disorders affecting several mammals
including humans, cattle, cervids, sheep, goats, and others [1–3]. These diseases are driven …

Prion diseases are fatal infectious neurodegenerative disorders in human and animals that
are caused by misfolding of the cellular prion protein (PrP C) into the infectious isoform PrP …

Prion diseases, also known as transmissible spongiform encephalopathies, are caused by
the accumulation of abnormal isoforms of the prion protein (scrapie isoform of the prion …

Prion diseases are a group of fatal neurodegenerative disorders that includes chronic
wasting disease, which affects cervids and is highly transmissible. Given that chronic …

Animal models are essential tools for investigating and understanding complex prion
diseases like chronic wasting disease (CWD), an infectious prion disease of cervids (elk …