Biophysical and structural investigations are presented with a focus on the membrane lipid
interactions of cationic linear antibiotic peptides such as magainin, PGLa, LL37, and melittin …

Even 30 years after the discovery of magainins, biophysical and structural investigations on
how these peptides interact with membranes can still bear surprises and add new …

The phylum Actinobacteria includes important human pathogens like Mycobacterium
tuberculosis and Corynebacterium diphtheriae and renowned producers of secondary …

The study of peptide-lipid and peptide-peptide interactions as well as their topology and
dynamics using biophysical and structural approaches have changed our view how …

Mixtures of the frog peptides magainin 2 and PGLa are well-known for their pronounced
synergistic killing of Gram-negative bacteria. We aimed to gain insight into the underlying …

The urgent global health challenge posed by methicillin-resistant Staphylococcus aureus
(MRSA) infections demands effective solutions. Antimicrobial peptides (AMPs) represent …

Temporin-GHc (GHc) and temporin-GHd (GHd) produced by the frog Hylarana guentheri
had shown broad-spectrum antibacterial activities against bacteria and fungi. In this study …

The antimicrobial peptide LyeTxI isolated from the venom of the spider Lycosa
erythrognatha is a potential model to develop new antibiotics against bacteria and fungi. In …

Infectious diseases and the rapid development of pathogens resistant to conventional drugs
are a serious global public health problem, which motivates the search for new …

Gene transfer using lentiviral vectors has therapeutic applications spanning from monogenic
and infectious diseases to cancer. Such gene therapy has to be improved by enhancing the …