Simple, efficient and thorough shotgun proteomic analysis with PatternLab V

MDM Santos, DB Lima, JSG Fischer, MA Clasen… - Nature protocols, 2022 - nature.com
Shotgun proteomics aims to identify and quantify the thousands of proteins in complex
mixtures such as cell and tissue lysates and biological fluids. This approach uses liquid …

Making the case for disordered proteins and biomolecular condensates in bacteria

MC Cohan, RV Pappu - Trends in Biochemical Sciences, 2020 - cell.com
Intrinsically disordered proteins/regions (IDPs/IDRs) contribute to a diverse array of
molecular functions in eukaryotic systems. There is also growing recognition that …

SepF is the FtsZ anchor in archaea, with features of an ancestral cell division system

N Pende, A Sogues, D Megrian, A Sartori-Rupp… - Nature …, 2021 - nature.com
Most archaea divide by binary fission using an FtsZ-based system similar to that of bacteria,
but they lack many of the divisome components described in model bacterial organisms …

Population genomics and antimicrobial resistance in Corynebacterium diphtheriae

M Hennart, LG Panunzi, C Rodrigues, Q Gaday… - Genome Medicine, 2020 - Springer
Background Corynebacterium diphtheriae, the agent of diphtheria, is a genetically diverse
bacterial species. Although antimicrobial resistance has emerged against several drugs …

Creating Polyploid Escherichia Coli and Its Application in Efficient L‐Threonine Production

S Wang, X Chen, X **, F Gu, W Jiang, Q Qi… - Advanced …, 2023 - Wiley Online Library
Prokaryotic genomes are generally organized in haploid. In synthetic biological research,
efficient chassis cells must be constructed to produce bio‐based products. Here, the …

Tip extension and simultaneous multiple fission in a filamentous bacterium

S Chimileski, GG Borisy, FE Dewhirst… - Proceedings of the …, 2024 - pnas.org
Organisms display an immense variety of shapes, sizes, and reproductive strategies. At
microscopic scales, bacterial cell morphology and growth dynamics are adaptive traits that …

Single-molecule imaging reveals that Z-ring condensation is essential for cell division in Bacillus subtilis

GR Squyres, MJ Holmes, SR Barger… - Nature …, 2021 - nature.com
Although many components of the cell division machinery in bacteria have been identified,,
the mechanisms by which they work together to divide the cell remain poorly understood …

Models versus pathogens: how conserved is the FtsZ in bacteria?

RR Battaje, R Piyush, V Pratap, D Panda - Bioscience Reports, 2023 - portlandpress.com
Combating anti-microbial resistance by develo** alternative strategies is the need of the
hour. Cell division, particularly FtsZ, is being extensively studied for its potential as an …

An Arg/Ala-rich helix in the N-terminal region of M. tuberculosis FtsQ is a potential membrane anchor of the Z-ring

ST Smrt, CA Escobar, S Dey, TA Cross… - Communications …, 2023 - nature.com
Mtb infects a quarter of the worldwide population. Most drugs for treating tuberculosis target
cell growth and division. With rising drug resistance, it becomes ever more urgent to better …

The archaeal protein SepF is essential for cell division in Haloferax volcanii

P Nußbaum, M Gerstner, M Dingethal, C Erb… - Nature …, 2021 - nature.com
In most bacteria, cell division depends on the tubulin homolog FtsZ and other proteins, such
as SepF, that form a complex termed the divisome. Cell division also depends on FtsZ in …