[HTML][HTML] Malaria gametocytogenesis

DA Baker - Molecular and biochemical parasitology, 2010 - Elsevier
Male and female gametocytes are the components of the malaria parasite life cycle which
are taken up from an infected host bloodstream by mosquitoes and thus mediate disease …

The Apicomplexan AP2 family: integral factors regulating Plasmodium development

HJ Painter, TL Campbell, M Llinás - Molecular and biochemical …, 2011 - Elsevier
Malaria is caused by protozoan parasites of the genus Plasmodium and involves infection of
multiple hosts and cell types during the course of an infection. To complete its complex life …

Strand-specific RNA sequencing in Plasmodium falciparum malaria identifies developmentally regulated long non-coding RNA and circular RNA

KM Broadbent, JC Broadbent, U Ribacke, D Wirth… - BMC genomics, 2015 - Springer
Background The human malaria parasite Plasmodium falciparum has a complex and multi-
stage life cycle that requires extensive and precise gene regulation to allow invasion and …

H2A.Z Demarcates Intergenic Regions of the Plasmodium falciparum Epigenome That Are Dynamically Marked by H3K9ac and H3K4me3

R Bártfai, WAM Hoeijmakers… - PLoS …, 2010 - journals.plos.org
Epigenetic regulatory mechanisms and their enzymes are promising targets for malaria
therapeutic intervention; however, the epigenetic component of gene expression in P …

“Recycling” classical drugs for malaria

C Teixeira, N Vale, B Perez, A Gomes… - Chemical …, 2014 - ACS Publications
Malaria has been a human health concern ever since the dawn of mankind, but despite the
huge struggles made to date to fight this infection, in 2012 over half a million people were …

From Genes to Transcripts, a Tightly Regulated Journey in Plasmodium

T Hollin, KG Le Roch - Frontiers in cellular and infection microbiology, 2020 - frontiersin.org
Over the past decade, we have witnessed significant progresses in understanding gene
regulation in Apicomplexa including the human malaria parasite, Plasmodium falciparum …

[HTML][HTML] Effect of clinically approved HDAC inhibitors on Plasmodium, Leishmania and Schistosoma parasite growth

MJ Chua, MSJ Arnold, W Xu, J Lancelot… - International Journal for …, 2017 - Elsevier
Malaria, schistosomiasis and leishmaniases are among the most prevalent tropical parasitic
diseases and each requires new innovative treatments. Targeting essential parasite …

HDAC inhibitors in parasitic diseases

KT Andrews, A Haque, MK Jones - Immunology and cell …, 2012 - Wiley Online Library
Parasitic diseases cause significant global morbidity and mortality, particularly in
underdeveloped regions of the world. Malaria alone causes∼ 800 000 deaths each year …

Epigenetic inhibitors target multiple stages of Plasmodium falciparum parasites

N Coetzee, H von Grüning, D Opperman… - Scientific reports, 2020 - nature.com
The epigenome of the malaria parasite, Plasmodium falciparum, is associated with
regulation of various essential processes in the parasite including control of proliferation …

Artemisinin resistance in Plasmodium falciparum is associated with an altered temporal pattern of transcription

S Mok, M Imwong, MJ Mackinnon, J Sim, R Ramadoss… - BMC genomics, 2011 - Springer
Abstract Background Artemisinin resistance in Plasmodium falciparum malaria has emerged
in Western Cambodia. This is a major threat to global plans to control and eliminate malaria …