Wnt/β-catenin signaling in cancers and targeted therapies
F Yu, C Yu, F Li, Y Zuo, Y Wang, L Yao, C Wu… - … and Targeted Therapy, 2021 - nature.com
Wnt/β-catenin signaling has been broadly implicated in human cancers and experimental
cancer models of animals. Aberrant activation of Wnt/β-catenin signaling is tightly linked with …
cancer models of animals. Aberrant activation of Wnt/β-catenin signaling is tightly linked with …
WNT signaling in cardiac and vascular disease
WNT signaling is an elaborate and complex collection of signal transduction pathways
mediated by multiple signaling molecules. WNT signaling is critically important for …
mediated by multiple signaling molecules. WNT signaling is critically important for …
[HTML][HTML] Circular RNA ITCH has inhibitory effect on ESCC by suppressing the Wnt/β-catenin pathway
Circular RNAs with exonic sequences represent a special form of non-coding RNAs,
discovered by analyzing a handful of transcribed genes. It has been observed that circular …
discovered by analyzing a handful of transcribed genes. It has been observed that circular …
Long non-coding RNAs are emerging targets of phytochemicals for cancer and other chronic diseases
The long non-coding RNAs (lncRNAs) are the crucial regulators of human chronic diseases.
Therefore, approaches such as antisense oligonucleotides, RNAi technology, and small …
Therefore, approaches such as antisense oligonucleotides, RNAi technology, and small …
Natural products for the management and prevention of breast cancer
Among all types of cancer, breast cancer is one of the most challenging diseases, which is
responsible for a large number of cancer related deaths. Hormonal therapy, surgery …
responsible for a large number of cancer related deaths. Hormonal therapy, surgery …
[HTML][HTML] The evolving roles of canonical WNT signaling in stem cells and tumorigenesis: implications in targeted cancer therapies
K Yang, X Wang, H Zhang, Z Wang, G Nan, Y Li… - Laboratory …, 2016 - Elsevier
The canonical WNT/β-catenin signaling pathway governs a myriad of biological processes
underlying the development and maintenance of adult tissue homeostasis, including …
underlying the development and maintenance of adult tissue homeostasis, including …
Recent advances in phytochemical based nano-drug delivery systems to combat breast cancer: A review
Breast Cancer is the most common cancer in women worldwide. Recently bioactive plant
products, namely phytochemicals are being been explored by researchers for their …
products, namely phytochemicals are being been explored by researchers for their …
Role of silymarin in cancer treatment: facts, hypotheses, and questions
The flavonoid silymarin extracted from the seeds of Sylibum marianum is a mixture of 6
flavolignan isomers. The 3 more important isomers are silybin (or silibinin), silydianin, and …
flavolignan isomers. The 3 more important isomers are silybin (or silibinin), silydianin, and …
[HTML][HTML] Wnt signaling and hepatocarcinogenesis: molecular targets for the development of innovative anticancer drugs
F Pez, A Lopez, M Kim, JR Wands, CC de Fromentel… - Journal of …, 2013 - Elsevier
Hepatocellular carcinoma (HCC) is one of the most common causes of cancer death
worldwide. HCC can be cured by radical therapies if early diagnosis is done while the tumor …
worldwide. HCC can be cured by radical therapies if early diagnosis is done while the tumor …
Mechanistic insights into the pharmacological significance of silymarin
Medicinal plants are considered the reservoir of diverse therapeutic agents and have been
traditionally employed worldwide to heal various ailments for several decades. Silymarin is a …
traditionally employed worldwide to heal various ailments for several decades. Silymarin is a …