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A brave new world of RNA-binding proteins
RNA-binding proteins (RBPs) are typically thought of as proteins that bind RNA through one
or multiple globular RNA-binding domains (RBDs) and change the fate or function of the …
or multiple globular RNA-binding domains (RBDs) and change the fate or function of the …
[HTML][HTML] Non-coding RNAs in development and disease: background, mechanisms, and therapeutic approaches
J Beermann, MT Piccoli, J Viereck… - Physiological …, 2016 - journals.physiology.org
Advances in RNA-sequencing techniques have led to the discovery of thousands of non-
coding transcripts with unknown function. There are several types of non-coding linear …
coding transcripts with unknown function. There are several types of non-coding linear …
Exploring epigenomic datasets by ChIPseeker
Q Wang, M Li, T Wu, L Zhan, L Li, M Chen… - Current …, 2022 - Wiley Online Library
In many aspects of life, epigenetics, or the altering of phenotype without changes in
sequences, play an essential role in biological function. A vast number of epigenomic …
sequences, play an essential role in biological function. A vast number of epigenomic …
Proteogenomic characterization reveals therapeutic vulnerabilities in lung adenocarcinoma
To explore the biology of lung adenocarcinoma (LUAD) and identify new therapeutic
opportunities, we performed comprehensive proteogenomic characterization of 110 tumors …
opportunities, we performed comprehensive proteogenomic characterization of 110 tumors …
Undulating changes in human plasma proteome profiles across the lifespan
Aging is a predominant risk factor for several chronic diseases that limit healthspan.
Mechanisms of aging are thus increasingly recognized as potential therapeutic targets …
Mechanisms of aging are thus increasingly recognized as potential therapeutic targets …
Proteomics identifies new therapeutic targets of early-stage hepatocellular carcinoma
Y Jiang, A Sun, Y Zhao, W Ying, H Sun, X Yang, B ** …
Pan-cancer computational histopathology reveals mutations, tumor composition and prognosis
We use deep transfer learning to quantify histopathological patterns across 17,355
hematoxylin and eosin-stained histopathology slide images from 28 cancer types and …
hematoxylin and eosin-stained histopathology slide images from 28 cancer types and …
MIENTURNET: an interactive web tool for microRNA-target enrichment and network-based analysis
Background miRNAs regulate the expression of several genes with one miRNA able to
target multiple genes and with one gene able to be simultaneously targeted by more than …
target multiple genes and with one gene able to be simultaneously targeted by more than …
Lung adenocarcinoma and lung squamous cell carcinoma cancer classification, biomarker identification, and gene expression analysis using overlap** feature …
JW Chen, J Dhahbi - Scientific reports, 2021 - nature.com
Lung cancer is one of the deadliest cancers in the world. Two of the most common subtypes,
lung adenocarcinoma (LUAD) and lung squamous cell carcinoma (LUSC), have drastically …
lung adenocarcinoma (LUAD) and lung squamous cell carcinoma (LUSC), have drastically …
Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways
Neuroticism is an important risk factor for psychiatric traits, including depression, anxiety,,
and schizophrenia,–. At the time of analysis, previous genome-wide association studies …
and schizophrenia,–. At the time of analysis, previous genome-wide association studies …