Machine perfusion preservation versus static cold storage for deceased donor kidney transplantation

SJ Tingle, RS Figueiredo, JAG Moir… - Cochrane Database …, 2019 - cochranelibrary.com
Background Kidney transplantation is the optimal treatment for end‐stage kidney disease.
Retrieval, transport and transplant of kidney grafts causes ischaemia reperfusion injury. The …

Transplanting marginal organs in the era of modern machine perfusion and advanced organ monitoring

T Resch, B Cardini, R Oberhuber… - Frontiers in …, 2020 - frontiersin.org
Organ transplantation is undergoing profound changes. Contraindications for donation have
been revised in order to better meet the organ demand. The use of lower-quality organs and …

Hypothermic machine perfusion is superior to static cold storage in deceased donor kidney transplantation: A meta‐analysis

SJ Tingle, RS Figueiredo, JAG Moir… - Clinical …, 2020 - Wiley Online Library
Background There remains a lack of consensus on the optimal storage method for deceased
donor kidneys. This meta‐analysis compares storage with hypothermic machine perfusion …

Effect of perioperative dexmedetomidine on delayed graft function following a donation-after-cardiac-death kidney transplant: a randomized clinical trial

X Shan, L Hu, Y Wang, H Liu, J Chen, X Meng… - JAMA network …, 2022 - jamanetwork.com
Importance Delayed graft function (DGF) is a risk factor for acute rejection and graft failure
after kidney transplant. Previous studies have suggested that dexmedetomidine may be …

Extracellular vesicles derived from mesenchymal stromal cells delivered during hypothermic oxygenated machine perfusion repair ischemic/reperfusion damage of …

T Rampino, M Gregorini, G Germinario, EF Pattonieri… - Biology, 2022 - mdpi.com
Simple Summary In this study, we explore for the first time an innovative tool for organ
preservation aimed to preventing ischemia reperfusion injury (IRI) in marginal kidneys from …

Hypothermic machine perfusion versus static cold storage in deceased donor kidney transplantation: a systematic review and meta‐analysis of randomized controlled …

P Peng, Z Ding, Y He, J Zhang, X Wang… - Artificial organs, 2019 - Wiley Online Library
Static cold storage (SCS) and hypothermic machine perfusion (HMP) are two primary
options for renal allograft preservation. Compared with SCS, HMP decreased the incidence …

Ex vivo kidney machine perfusion: meta-analysis of randomized clinical trials

M Kang, S Kim, JY Choi, KS Kim, YK Jung… - British Journal of …, 2024 - academic.oup.com
Background Machine perfusion is an organ preservation strategy used to improve function
over simple storage in a cold environment. This article presents an updated systematic …

[HTML][HTML] Preventing rejection of the kidney transplant

D Malhotra, P Jethwani - Journal of Clinical Medicine, 2023 - mdpi.com
With increasing knowledge of immunologic factors and with the advent of potent
immunosuppressive agents, the last several decades have seen significantly improved …

[HTML][HTML] Machine perfusion for abdominal organ preservation: a systematic review of kidney and liver human grafts

MI Bellini, M Nozdrin, J Yiu, V Papalois - Journal of Clinical Medicine, 2019 - mdpi.com
Introduction: To match the current organ demand with organ availability from the donor pool,
there has been a shift towards acceptance of extended criteria donors (ECD), often …

Exploring the causes of the high incidence of delayed graft function after kidney transplantation in Brazil: a multicenter study

TV de Sandes‐Freitas, M Mazzali… - Transplant …, 2021 - Wiley Online Library
Summary This retrospective multicenter (n= 18) cohort study evaluated the incidence, risk
factors, and the impact of delayed graft function (DGF) on 1‐year kidney transplant (KT) …