Studies in diverse biological systems have indicated that host–parasite co-evolution is
responsible for the extraordinary genetic diversity seen in some genomic regions, such as …

The idea that individual differences in behavior and physiology can be partly understood by
linking them to a fast-slow continuum of life history strategies has become popular in the …

Age is a common risk factor in many diseases, but the molecular basis for this relationship is
elusive. In this study we identified four disease clusters from 116 diseases in UK Biobank …

Balancing selection is an evolutionary process that maintains genetic polymorphisms at
selected loci and strongly reduces the likelihood of allele fixation. When allelic …

The identification of genomic regions and genes that have evolved under natural selection is
a fundamental objective in the field of evolutionary genetics. While various approaches have …

Recent studies of cosmopolitan Drosophila populations have found hundreds to thousands
of genetic loci with seasonally fluctuating allele frequencies, bringing temporally fluctuating …

Several decades of research have convincingly shown that classical human leukocyte
antigen (HLA) loci bear signatures of natural selection. Despite this conclusion, many …

Structural variation (SV) is a large difference (typically> 100 bp) in the genomic structure of
two genomes and includes both copy number variation and variation that does not change …

Characterizing the population history of a species and identifying loci underlying local
adaptation is crucial in functional ecology, evolutionary biology, conservation and …

The ability of populations to expand their geographical ranges, whether as invaders,
agricultural strains or climate migrants, is currently one of the most serious global problems …