Influence of particle properties on powder bulk behaviour and processability

UV Shah, V Karde, C Ghoroi, JYY Heng - International journal of …, 2017 - Elsevier
Understanding interparticle interactions in powder systems is crucial to pharmaceutical
powder processing. Nevertheless, there remains a great challenge in identifying the key …

Sticking and picking in pharmaceutical tablet compression: an IQ consortium review

S Chattoraj, P Daugherity, T McDermott… - Journal of …, 2018 - Elsevier
Sticking and picking during tablet manufacture has received increasing interest recently, as
it causes tablet defects, downtime in manufacturing, and yield losses. The capricious nature …

Particle engineering in pharmaceutical solids processing: surface energy considerations

DR Williams - Current pharmaceutical design, 2015 - ingentaconnect.com
During the past 10 years particle engineering in the pharmaceutical industry has become a
topic of increasing importance. Engineers and pharmacists need to understand and control …

Effect of milling temperatures on surface area, surface energy and cohesion of pharmaceutical powders

UV Shah, Z Wang, D Olusanmi, AS Narang… - International journal of …, 2015 - Elsevier
Particle bulk and surface properties are influenced by the powder processing routes. This
study demonstrates the effect of milling temperatures on the particle surface properties …

Monitoring the Surface Energy Change of Nanoparticles in Functionalization Reactions with the NanoTraPPED Method

A Honciuc, OI Negru - Nanomaterials, 2023 - mdpi.com
Performing chemical functionalization on the surface of nanoparticles underlies their use in
applications. Probing that a physicochemical transformation has indeed occurred on a …

Toward a molecular understanding of the impact of crystal size and shape on punch sticking

S Paul, LJ Taylor, B Murphy, JF Krzyzaniak… - Molecular …, 2020 - ACS Publications
Punch sticking during tablet manufacturing is a common problem facing the pharmaceutical
industry. Using several model compounds, effects of crystal size and shape of active …

Interfacial phenomena

E Hadjittofis, SC Das, GGZ Zhang, JYY Heng - Develo** solid oral …, 2017 - Elsevier
The surface of a pharmaceutical solid has a direct implication on a wide range interfacial
phenomena affecting powder processing, handling, and performance. This chapter employs …

NanoTraPPED—A New Method for Determining the Surface Energy of Nanoparticles via Pickering Emulsion Polymerization

A Honciuc, OI Negru - Nanomaterials, 2021 - mdpi.com
Surface energy with its polar and disperse components describes the physicochemical state
of nanoparticles'(NPs) surfaces, and can be a valuable parameter for predicting their bulk …

The effect of polymorphism on surface energetics of D-mannitol polymorphs

RR Smith, UV Shah, JV Parambil, DJ Burnett… - The AAPS journal, 2017 - Springer
The aim of this work was to assess the effect of different crystalline polymorphism on surface
energetics of D-mannitol using finite dilution inverse gas chromatography (FD-IGC). Pure α …

Measuring the sticking of mefenamic acid powders on stainless steel surface

Z Wang, UV Shah, D Olusanmi, AS Narang… - International journal of …, 2015 - Elsevier
This study proposes an approach for quantifying the amount of pharmaceutical powder
adhering (quality attribute) to the metals surfaces. The effect of surface roughness …