Biological effects of metal-based nanomaterials for tumor metalloimmunotherapy

H Lei, G Hou, M Chen, J Ji, L Cheng - Nano Today, 2023 - Elsevier
Tumor immunotherapy as a new tumor therapy has been intensively studied and reported.
However, the expected utilization and therapeutic effects have not been achieved due to the …

Manipulating calcium homeostasis with nanoplatforms for enhanced cancer therapy

Y Feng, J Wang, J Cao, F Cao, X Chen - Exploration, 2024 - Wiley Online Library
Abstract Calcium ions (Ca2+) are indispensable and versatile metal ions that play a pivotal
role in regulating cell metabolism, encompassing cell survival, proliferation, migration, and …

Enrichment and sensing tumor cells by embedded immunomodulatory DNA hydrogel to inhibit postoperative tumor recurrence

D Wang, J Liu, J Duan, H Yi, J Liu, H Song… - Nature …, 2023 - nature.com
Postoperative tumor recurrence and metastases often lead to cancer treatment failure. Here,
we develop a local embedded photodynamic immunomodulatory DNA hydrogel for early …

Cascade Carrier‐Free Nanoparticles Forming In Situ Nanovaccines for Synergistic Photothermal‐Immunotherapy of Cancer

C Huang, H Wang, X Yang, Q Yu… - Advanced Functional …, 2024 - Wiley Online Library
Rapid advances in nanotechnology have made it possible to combine photothermal therapy
(PTT) with immunotherapy, enabling to activate an in situ vaccine effect. However, this effect …

Immunomodulatory metal-based biomaterials for cancer immunotherapy

K Yuan, C Zhang, X Pan, B Hu, J Zhang… - Journal of Controlled …, 2024 - Elsevier
Cancer immunotherapy, as an emerging cancer treatment approach, harnesses the patient's
own immune system to effectively prevent tumor recurrence or metastasis. However, its …

Engineered macrophage-derived cellular vesicles for NIR-II fluorescence imaging-guided precise cancer photo-immunotherapy

Q Lin, Y Wang, L Wang, Z Fan - Colloids and Surfaces B: Biointerfaces, 2024 - Elsevier
Significant progress has been made in cancer immunotherapy; however, challenges such
as interpatient variability, limited treatment response, and severe side effects persist …

Nanodelivery systems as a novel strategy to Overcome treatment failure of cancer

S He, X Gou, S Zhang, X Zhang, H Huang… - Small …, 2024 - Wiley Online Library
Despite the tremendous progress in cancer treatment in recent decades, cancers often
become resistant due to multiple mechanisms, such as intrinsic or acquired multidrug …

Engineering Semiconducting Polymeric Nanoagonists Potentiate cGAS‐STING Pathway Activation and Elicit Long Term Memory Against Recurrence in Breast …

H Yuan, C Qiu, X Wang, P Wang, L Yi… - Advanced …, 2025 - Wiley Online Library
Triple‐negative breast cancer has an immunologically “cold” microenvironment, which leads
to resistance to current immunotherapy. The activation of stimulator of interferon genes …

Dual and multi-immune activation strategies for emerging cancer immunotherapy

Y Zhang, L Liu, H He, Y Sun, Z Zhong - Materials Today, 2024 - Elsevier
Cancer immunotherapy is revolutionizing clinical oncology and prosperously advanced by
immune agonists that boost immune stimulation. In recent years, nano-agonists with tunable …

Manganese Ions Chelated Tumosomes as Autologous Cancer Nanovaccines for Effective Suppression of Postsurgical Tumor Relapse

M Chen, Y Hao, S Ling, H Yang, Q Li, Y Wu, C Wang… - ACS …, 2025 - ACS Publications
Autologous cancer vaccines represent a promising strategy to effectively suppress
postoperative tumor relapse by eliciting tumor-specific immune responses that highly rely on …