Progesterone is a highly lipophilic gonadal hormone that can influence behavior and mental
health through its receptors in the brain. Fluctuations in progesterone levels across critical …

Many different forms of hormonal contraception are used by millions of women worldwide.
These contraceptives differ in the dose and type of synthetic progestogenic compound …

The glucocorticoid receptor (GR) regulates transcription of genes involved in multiple
processes. Medroxyprogesterone acetate (MPA), widely used in the injectable contraceptive …

Progestins used in hormonal contraceptives and menopausal hormone therapy (MHT) have
been linked to increased breast cancer risk. Whether the association holds for all progestins …

Hormonal contraception exposes women to synthetic progesterone receptor (PR) agonists,
progestins, and transiently increases breast cancer risk. How progesterone and progestins …

Studies directly comparing the efficacies and potencies of multiple progestins used in
contraception and menopausal hormone therapy (MHT) in parallel via human progesterone …

Progestins (synthetic progestogens) are progesterone receptor (PR) ligands used globally
by women in both hormonal contraception and menopausal hormone therapy. Although four …

Hormonal contraceptives (HCs) and hormone replacement therapy (HRT) are therapies
designed to target the progesterone receptor (PR) to prevent unwanted pregnancy and to …

Introduction: Hormones influence women's health and athletic performance, managing
conditions like menstrual irregularities, menopause, and osteoporosis. Therapies such as …

Obesity and progestins which are used in contraception and menopausal hormone therapy
are known risk factors for breast cancer. However, the precise mechanisms by which these …