Biosensing with dnazymes

EM McConnell, I Cozma, Q Mou, JD Brennan… - Chemical Society …, 2021 - pubs.rsc.org
This article provides a comprehensive review of biosensing with DNAzymes, providing an
overview of different sensing applications while highlighting major progress and seminal …

DNAzyme-based biosensors: Immobilization strategies, applications, and future prospective

S Khan, B Burciu, CDM Filipe, Y Li, K Dellinger… - Acs Nano, 2021 - ACS Publications
Since their discovery almost three decades ago, DNAzymes have been used extensively in
biosensing. Depending on the type of DNAzyme being used, these functional …

Detection of SARS-CoV-2 viral particles using direct, reagent-free electrochemical sensing

H Yousefi, A Mahmud, D Chang, J Das… - Journal of the …, 2021 - ACS Publications
The development of new methods for direct viral detection using streamlined and ideally
reagent-free assays is a timely and important, but challenging, problem. The challenge of …

Functional nucleic acid biosensors utilizing rolling circle amplification

RM Bialy, A Mainguy, Y Li, JD Brennan - Chemical Society Reviews, 2022 - pubs.rsc.org
Functional nucleic acids (FNAs), including DNA aptamers and DNAzymes, are finding
increasing use as molecular recognition elements for point-of-care (POC) assays and …

Functional nucleic acids for pathogenic bacteria detection

D Chang, S Zakaria, S Esmaeili Samani… - Accounts of Chemical …, 2021 - ACS Publications
Conspectus Pathogens have long presented a significant threat to human lives, and hence
the rapid detection of infectious pathogens is vital for improving human health. Current …

A Colorimetric Biosensing Platform with Aptamers, Rolling Circle Amplification and Urease‐Mediated Litmus Test

D Chang, J Li, R Liu, M Liu, K Tram… - Angewandte …, 2023 - Wiley Online Library
Here we report on an ultra‐sensitive colorimetric sensing platform that takes advantage of
both the strong amplification power of rolling circle amplification (RCA) and the high …

Au@ Pd nanopopcorn and aptamer nanoflower assisted lateral flow strip for thermal detection of exosomes

N Cheng, Y Song, Q Shi, D Du, D Liu, Y Luo… - Analytical …, 2019 - ACS Publications
Conventional lateral flow biosensing technologies face the dual formidable challenges of
poor sensitivity and cumbersome quantitative devices. Here, we developed a Au@ Pd …

Engineering a ligase binding DNA aptamer into a templating DNA scaffold to guide the selective synthesis of circular DNAzymes and DNA aptamers

Y Yan, D Chang, Y Xu, Y Chang, Q Zhang… - Journal of the …, 2023 - ACS Publications
Functional nucleic acids (FNAs), such as DNAzymes and DNA aptamers, can be engineered
into circular forms for improved performance. Circular FNAs are promising candidates for …

A DNA Nanoflower‐Assisted Separation‐Free Nucleic Acid Detection Platform with a Commercial Pregnancy Test Strip

L Qi, M Yang, D Chang, W Zhao, S Zhang… - Angewandte …, 2021 - Wiley Online Library
There is a constant drive for affordable point‐of‐care testing (POCT) technologies for the
detection of infectious human diseases. Herein, we report a simple platform for DNA …

Enzymatical biomineralization of DNA nanoflowers mediated by manganese ions for tumor site activated magnetic resonance imaging

H Zhao, J Lv, F Li, Z Zhang, C Zhang, Z Gu, D Yang - Biomaterials, 2021 - Elsevier
DNA nanoflower has been demonstrated as a promising DNA nanostructure for therapeutics
and bioimaging primarily because of the programmable DNA sequence and unique …