Application of noninvasive vagal nerve stimulation to stress-related psychiatric disorders

JD Bremner, NZ Gurel, MT Wittbrodt… - Journal of personalized …, 2020 - mdpi.com
Background: Vagal Nerve Stimulation (VNS) has been shown to be efficacious for the
treatment of depression, but to date, VNS devices have required surgical implantation, which …

Acute and long-term effects of COVID-19 on brain and mental health: A narrative review

JD Bremner, SJ Russo, R Gallagher… - Brain, behavior, and …, 2024 - Elsevier
Background COVID infection has been associated with long term sequalae (Long COVID)
which include neurological and behavioral effects in thousands of patients, but the etiology …

Transcutaneous cervical vagus nerve stimulation reduces behavioral and physiological manifestations of withdrawal in patients with opioid use disorder: a double …

AH Gazi, AB Harrison, TP Lambert, M Obideen, P Alavi… - Brain stimulation, 2022 - Elsevier
Abstract Background Opioid Use Disorder (OUD) is a serious public health problem, and the
behavioral and physiological effects of opioid withdrawal can be a major impediment to …

Robust estimation of respiratory variability uncovers correlates of limbic brain activity and transcutaneous cervical vagus nerve stimulation in the context of traumatic …

AH Gazi, MT Wittbrodt, AB Harrison… - IEEE Transactions …, 2021 - ieeexplore.ieee.org
Objective: Variations in respiration patterns are a characteristic response to distress due to
underlying neurorespiratory couplings. Yet, no work to date has quantified respiration …

Transcutaneous auricular vagus nerve stimulation and median nerve stimulation reduce acute stress in young healthy adults: A single-blind sham-controlled …

JA Sanchez-Perez, AH Gazi, FN Rahman… - Frontiers in …, 2023 - frontiersin.org
Stress is a major determinant of health and wellbeing. Conventional stress management
approaches do not account for the daily-living acute changes in stress that affect quality of …

Transcutaneous cervical vagal nerve stimulation reduces sympathetic responses to stress in posttraumatic stress disorder: A double-blind, randomized, sham …

NZ Gurel, MT Wittbrodt, H Jung, MMH Shandhi… - Neurobiology of …, 2020 - Elsevier
Objective Exacerbated autonomic responses to acute stress are prevalent in posttraumatic
stress disorder (PTSD). The purpose of this study was to assess the effects of …

Transcutaneous cervical vagal nerve stimulation in patients with posttraumatic stress disorder (PTSD): a pilot study of effects on PTSD symptoms and interleukin-6 …

JD Bremner, MT Wittbrodt, NZ Gurel… - Journal of affective …, 2021 - Elsevier
Background Posttraumatic stress disorder (PTSD) is a highly disabling condition associated
with alterations in multiple neurobiological systems, including increases in inflammatory and …

Transcutaneous cervical vagus nerve stimulation inhibits the reciprocal of the pulse transit time's responses to traumatic stress in posttraumatic stress disorder

AH Gazi, S Sundararaj, AB Harrison… - 2021 43rd Annual …, 2021 - ieeexplore.ieee.org
Research has shown that transcutaneous cervical vagus nerve stimulation (tcVNS) yields
downstream changes in peripheral physiology in individuals afflicted with posttraumatic …

A method to quantify autonomic nervous system function in healthy, able-bodied individuals

S Debnath, TJ Levy, M Bellehsen, RM Schwartz… - Bioelectronic …, 2021 - Springer
Background The autonomic nervous system (ANS) maintains physiological homeostasis in
various organ systems via parasympathetic and sympathetic branches. ANS function is …

Transcutaneous cervical vagus nerve stimulation lengthens exhalation in the context of traumatic stress

AH Gazi, S Sundararaj, AB Harrison… - 2021 IEEE EMBS …, 2021 - ieeexplore.ieee.org
Transcutaneous electrical stimulation of the vagus nerve is believed to deliver afferent
signaling to the brain that, in turn, yields downstream changes in peripheral physiology …