Post-translational modifications of sibling proteins and their roles in osteogenesis and dentinogenesis

C Qin, O Baba, WT Butler - Critical Reviews in Oral Biology …, 2004 - journals.sagepub.com
The extracellular matrix (ECM) of bone and dentin contains several non-collagenous
proteins. One category of non-collagenous protein is termed the SIBLING (S mall I ntegrin-B …

Hereditary dentine disorders: dentinogenesis imperfecta and dentine dysplasia

MJ Barron, ST McDonnell, I MacKie… - Orphanet journal of rare …, 2008 - Springer
The hereditary dentine disorders, dentinogenesis imperfecta (DGI) and dentine dysplasia
(DD), comprise a group of autosomal dominant genetic conditions characterised by …

Nucleation of apatite crystals in vitro by self-assembled dentin matrix protein 1

G He, T Dahl, A Veis, A George - Nature materials, 2003 - nature.com
Bones and teeth are biocomposites that require controlled mineral deposition during their
self-assembly to form tissues with unique mechanical properties. Acidic extracellular matrix …

Hereditary dentin defects

JW Kim, JP Simmer - Journal of dental research, 2007 - journals.sagepub.com
By the Shields classification, articulated over 30 years ago, inherited dentin defects are
divided into 5 types: 3 types of dentinogenesis imperfecta (DGI), and 2 types of dentin …

Importance of phosphorylation for osteopontin regulation of biomineralization

A Gericke, C Qin, L Spevak, Y Fujimoto… - Calcified tissue …, 2005 - Springer
Previous in vitro and in vivo studies demonstrated that osteopontin (OPN) is an inhibitor of
the formation and growth of hydroxyapatite (HA) and other biominerals. The present study …

Matrix macromolecules in hard tissues control the nucleation and hierarchical assembly of hydroxyapatite

S Gajjeraman, K Narayanan, J Hao, C Qin… - Journal of Biological …, 2007 - ASBMB
Biogenic minerals found in teeth and bones are synthesized by precise cell-mediated
mechanisms. They have superior mechanical properties due to their complex architecture …

The expression of dentin sialophosphoprotein gene in bone

C Qin, JC Brunn, E Cadena, A Ridall… - Journal of dental …, 2002 - journals.sagepub.com
Dentin sialoprotein (DSP) and dentin phosphoprotein (DPP) are expressed as a single
mRNA transcript coding for a large precursor protein termed dentin sialophosphoprotein …

Dentin matrix protein 1 immobilized on type I collagen fibrils facilitates apatite deposition in vitro

G He, A George - Journal of Biological Chemistry, 2004 - ASBMB
During bone and dentin mineralization, the crystal nucleation and growth processes are
considered to be matrix regulated. Osteoblasts and odontoblasts synthesize a polymeric …

DMP1 depletion decreases bone mineralization in vivo: an FTIR imaging analysis

Y Ling, HF Rios, ER Myers, Y Lu… - Journal of Bone and …, 2005 - academic.oup.com
The role of DMP1 in mineralization was analyzed by comparing bone mineral and matrix
properties in dmp1‐null female mice to heterozygous and wildtype controls by FTIR imaging …

Spatially and temporally controlled biomineralization is facilitated by interaction between self-assembled dentin matrix protein 1 and calcium phosphate nuclei in …

G He, S Gajjeraman, D Schultz, D Cookson, C Qin… - Biochemistry, 2005 - ACS Publications
Bone and dentin biomineralization are well-regulated processes mediated by extracellular
matrix proteins. It is widely believed that specific matrix proteins in these tissues modulate …