Secretion systems in Gram-negative bacteria: structural and mechanistic insights
Bacteria have evolved a remarkable array of sophisticated nanomachines to export various
virulence factors across the bacterial cell envelope. In recent years, considerable progress …
virulence factors across the bacterial cell envelope. In recent years, considerable progress …
Hydrophobicity: an ancient damage-associated molecular pattern that initiates innate immune responses
SY Seong, P Matzinger - Nature Reviews Immunology, 2004 - nature.com
It is currently thought that immune responses are initiated by pathogen-associated molecular
patterns or by tissue-derived danger/alarm signals. Here, we propose that these two groups …
patterns or by tissue-derived danger/alarm signals. Here, we propose that these two groups …
Type IV pilus structure and bacterial pathogenicity
Type IV pili are remarkably strong, flexible filaments with varied roles in bacterial
pathogenicity. All Gram-negative bacterial surfaces have type IV pili, which are polymeric …
pathogenicity. All Gram-negative bacterial surfaces have type IV pili, which are polymeric …
[BOOK][B] Microbial physiology
AG Moat, JW Foster, MP Spector - 2002 - books.google.com
The Fourth Edition of Microbial Physiology retains the logical, easy-to-follow organization of
the previous editions. An introduction to cell structure and synthesis of cell components is …
the previous editions. An introduction to cell structure and synthesis of cell components is …
Host–pathogen checkpoints and population bottlenecks in persistent and intracellular uropathogenic Escherichia coli bladder infection
Bladder infections affect millions of people yearly, and recurrent symptomatic infections
(cystitis) are very common. The rapid increase in infections caused by multidrug-resistant …
(cystitis) are very common. The rapid increase in infections caused by multidrug-resistant …
A comprehensive guide to pilus biogenesis in Gram-negative bacteria
Pili are crucial virulence factors for many Gram-negative pathogens. These surface
structures provide bacteria with a link to their external environments by enabling them to …
structures provide bacteria with a link to their external environments by enabling them to …
Animal Enterotoxigenic Escherichia coli
JD Dubreuil, RE Isaacson, DM Schifferli - EcoSal Plus, 2016 - Am Soc Microbiol
Enterotoxigenic Escherichia coli (ETEC) is the most common cause of E. coli diarrhea in
farm animals. ETEC are characterized by the ability to produce two types of virulence factors …
farm animals. ETEC are characterized by the ability to produce two types of virulence factors …
X-ray Structure of the FimC-FimH Chaperone-Adhesin Complex from Uropathogenic Escherichia coli
D Choudhury, A Thompson, V Stojanoff, S Langermann… - Science, 1999 - science.org
Type 1 pili—adhesive fibers expressed in most members of the Enterobacteriaceae family—
mediate binding to mannose receptors on host cells through the FimH adhesin. Pilus …
mediate binding to mannose receptors on host cells through the FimH adhesin. Pilus …
Receptor binding studies disclose a novel class of high‐affinity inhibitors of the Escherichia coli FimH adhesin
Mannose‐binding type 1 pili are important virulence factors for the establishment of
Escherichia coli urinary tract infections (UTIs). These infections are initiated by adhesion of …
Escherichia coli urinary tract infections (UTIs). These infections are initiated by adhesion of …
Structural basis of tropism of Escherichia coli to the bladder during urinary tract infection
The first step in the colonization of the human urinary tract by pathogenic Escherichia coli is
the mannose‐sensitive binding of FimH, the adhesin present at the tip of type 1 pili, to the …
the mannose‐sensitive binding of FimH, the adhesin present at the tip of type 1 pili, to the …