Salvia miltiorrhiza:(Danshen) is a significant (traditional Chinese medication) natural
remedy, enhancing blood circulation and clear blood stasis. In this view, it is widely used …

IL-1 belongs to a family of 11 members and is one of the seven receptor-agonists with pro-
inflammatory activity. Beyond its biological role as a regulator of the innate immune …

Virtually all patients with multiple myeloma become unresponsive to treatment over time.
Relapsed/refractory multiple myeloma (RRMM) is accompanied by the clonal evolution of …

Multiple myeloma (MM) is the second most common hematological malignancy of plasma
cells, characterized by osteolytic bone lesions, anemia, hypercalcemia, renal failure, and the …

Two mechanisms are involved in the immune escape of cancer cells: the immunoediting of
tumor cells and the suppression of the immune system. Both processes have been revealed …

Although inflammation is a host defense mechanism, chronic inflammation mediates several
diseases, including cancer, allergy, asthma, and autoimmune diseases, and reportedly, it is …

In addition to the genomic alterations that occur in malignant cells, the immune system is
increasingly appreciated as a critical axis that regulates the rise of neoplasms and the …

Multiple myeloma (MM), an incurable plasma cell cancer, represents the second most
prevalent hematological malignancy. Deregulated activity of the nuclear factor kappaB (NF …

Cancer patients experience a four-fold increase in thrombosis risk, indicating that cancer
development and progression are associated with platelet activation. Xenograft experiments …

Multiple myeloma is a B-cell lineage cancer in which neoplastic plasma cells expand in the
bone marrow and pathophysiological interactions with components of microenvironment …