Black Cumin (Nigella sativa L.): A Comprehensive Review on Phytochemistry, Health Benefits, Molecular Pharmacology, and Safety

MA Hannan, MA Rahman, AAM Sohag, MJ Uddin… - Nutrients, 2021 - mdpi.com
Mounting evidence support the potential benefits of functional foods or nutraceuticals for
human health and diseases. Black cumin (Nigella sativa L.), a highly valued nutraceutical …

Toxicology and pharmacology of synthetic organoselenium compounds: An update

CW Nogueira, NV Barbosa, JBT Rocha - Archives of Toxicology, 2021 - Springer
Here, we addressed the pharmacology and toxicology of synthetic organoselenium
compounds and some naturally occurring organoselenium amino acids. The use of …

Zingerone reduces sodium arsenite-induced nephrotoxicity by regulating oxidative stress, inflammation, apoptosis and histopathological changes

N Akaras, C Gur, S Kucukler, FM Kandemir - Chemico-biological …, 2023 - Elsevier
Arsenic is widely available in the environment and arsenic toxicity is a public health problem
of serious concern worldwide. Zingerone is a promising phytochemical with various …

Protective Effects of Black Cumin (Nigella sativa) and Its Bioactive Constituent, Thymoquinone against Kidney Injury: An Aspect on Pharmacological Insights

MA Hannan, MS Zahan, PP Sarker, A Moni… - International Journal of …, 2021 - mdpi.com
The prevalence of chronic kidney disease (CKD) is increasing worldwide, and a close
association between acute kidney injury (AKI) and CKD has recently been identified. Black …

Attenuation of sodium arsenite-induced cardiotoxicity and neurotoxicity with the antioxidant, anti-inflammatory, and antiapoptotic effects of hesperidin

M Kuzu, FM Kandemir, S Yıldırım, C Çağlayan… - … Science and Pollution …, 2021 - Springer
In the scope of the study, the protective effect of hesperidin (HES), a flavanone glycoside,
was investigated against sodium arsenite (NaAsO 2, SA) induced heart and brain toxicity …

Silver nanoparticles enhance oxidative stress, inflammation, and apoptosis in liver and kidney tissues: potential protective role of thymoquinone

B Salama, KJ Alzahrani, KS Alghamdi… - Biological trace element …, 2023 - Springer
Silver nanoparticles (AgNPs) are the most common nanomaterials in consumer products.
Therefore, it has been crucial to control AgNPs toxicological effects to improve their safety …

Chlorogenic acid prevents hepatotoxicity in arsenic-treated mice: role of oxidative stress and apoptosis

MA Dkhil, AE Abdel Moneim, AA Bauomy… - Molecular biology …, 2020 - Springer
Arsenic is a potent and toxic heavy metal found in the environment that causes health
problems, including liver disease, in humans and animals. Chlorogenic acid (CA) is the most …

Nephroprotective role of selenium nanoparticles against glycerol-induced acute kidney injury in rats

G AlBasher, S Alfarraj, S Alarifi, S Alkhtani… - Biological trace element …, 2020 - Springer
Acute kidney injury (AKI) is a clinical syndrome associated with the incidence of
rhabdomyolysis (RM). The current study was carried out to evaluate whether selenium …

[HTML][HTML] Protective effects of zingerone against sodium arsenite-induced lung toxicity: A multi-biomarker approach

H Şimşek, S Küçükler, C Gür, M İleritürk… - Iranian Journal of …, 2023 - ncbi.nlm.nih.gov
Objective (s): Sodium arsenite (SA) exposure is toxic to the body. Zingerone (ZNG) is a
flavonoid with many biological properties found naturally in honey and plants. This study …

Protective efficacy of thymoquinone or ebselen separately against arsenic-induced hepatotoxicity in rat

D Al Aboud, RS Baty, KF Alsharif, KE Hassan… - … Science and Pollution …, 2021 - Springer
Arsenic (As) exposure is associated with adverse health outcomes to the living organisms. In
the present study, the hepato-protective ability of thymoquinone (TQ), the active principle of …