Skeletal muscle regeneration is highly dependent on the inflammatory response. A wide
variety of innate and adaptive immune cells orchestrate the complex process of muscle …

Extracellular vesicles (EVs) are small lipid bilayer-delimited particles that are naturally
released from cells into body fluids, and therefore can travel and convey regulatory functions …

Mesenchymal stromal cell-derived extracellular vesicles (MSC-EVs) are extensively studied
as therapeutic tools. Evaluation of their biodistribution is fundamental to understanding MSC …

Skeletal muscle tissue cannot repair itself after volumetric muscle loss (VML) injury, which
results in chronic inflammation and secondary injuries. Quercetin (QCN) possesses natural …

Cellular nanovesicles which are referred to as cell-derived, nanosized lipid bilayer
structures, have emerged as a promising platform for regulating immune responses. Owing …

Volumetric muscle loss (VML) is an acute trauma that results in persistent inflammation,
supplantation of muscle tissue with fibrotic scarring, and decreased muscle function. The cell …

Tendinopathy, a common degenerative condition among athletes and middle-aged
individuals, leads to pain and functional limitations. Traditional treatments focus on symptom …

Perinatal tissues, such as placenta and umbilical cord contain a variety of somatic stem cell
types, spanning from the largely used hematopoietic stem and progenitor cells to the most …

The extracellular microenvironment regulates many of the mechanical and biochemical cues
that direct musculoskeletal development and are involved in musculoskeletal disease. The …

Oxidative stress and fibrosis are important stress responses that characterize
bronchopulmonary dysplasia (BPD), a disease for which only a therapy but not a cure has …