Role of non‐coding variants in cardiovascular disease
K Heshmatzad, N Naderi, M Maleki… - Journal of Cellular …, 2023 - Wiley Online Library
Cardiovascular diseases (CVDs) constitute one of the significant causes of death worldwide.
Different pathological states are linked to CVDs, which despite interventions and treatments …
Different pathological states are linked to CVDs, which despite interventions and treatments …
Loneliness and depression: bidirectional mendelian randomization analyses using data from three large genome-wide association studies
Major depression (MD) is a serious psychiatric illness afflicting nearly 5% of the world's
population. A large correlational literature suggests that loneliness is a prospective risk …
population. A large correlational literature suggests that loneliness is a prospective risk …
Cardiovascular disease risk in people with severe mental disorders: an update and call for action
L Rødevand, M Tesli… - Current Opinion in …, 2022 - journals.lww.com
The level of CVD comorbidity remains high in SMDs, indicating that most people with SMDs
have not benefitted from recent medical advances. A complex interplay between genetic and …
have not benefitted from recent medical advances. A complex interplay between genetic and …
Shared genetic loci between schizophrenia and white blood cell counts suggest genetically determined systemic immune abnormalities
Background Immune mechanisms are indicated in schizophrenia (SCZ). Recent genome-
wide association studies (GWAS) have identified genetic variants associated with SCZ and …
wide association studies (GWAS) have identified genetic variants associated with SCZ and …
Psychiatric disorders and subsequent risk of cardiovascular disease: a longitudinal matched cohort study across three countries
Q Shen, DH Mikkelsen, LB Luitva, H Song… - …, 2023 - thelancet.com
Background Several psychiatric disorders have been associated with increased risk of
cardiovascular disease (CVD), however, the role of familial factors and the main disease …
cardiovascular disease (CVD), however, the role of familial factors and the main disease …
Extensive bidirectional genetic overlap between bipolar disorder and cardiovascular disease phenotypes
Patients with bipolar disorder (BIP) have a high risk of cardiovascular disease (CVD),
despite considerable individual variation. The mechanisms underlying comorbid CVD in BIP …
despite considerable individual variation. The mechanisms underlying comorbid CVD in BIP …
Breaking the vicious cycle: The interplay between loneliness, metabolic illness, and mental health
M Ahmed, I Cerda, M Maloof - Frontiers in Psychiatry, 2023 - frontiersin.org
Loneliness, or perceived social isolation, is a leading predictor of all-cause mortality and is
increasingly considered a public health epidemic afflicting significant portions of the general …
increasingly considered a public health epidemic afflicting significant portions of the general …
Genome-wide analysis of schizophrenia and multiple sclerosis identifies shared genomic loci with mixed direction of effects
Common genetic variants identified in genome-wide association studies (GWAS) show
varying degrees of genetic pleiotropy across complex human disorders. Clinical studies of …
varying degrees of genetic pleiotropy across complex human disorders. Clinical studies of …
[HTML][HTML] Prominent health problems, socioeconomic deprivation, and higher brain age in lonely and isolated individuals: A population-based study
Loneliness is linked to increased risk for Alzheimer's disease, but little is known about
factors potentially contributing to adverse brain health in lonely individuals. In this study, we …
factors potentially contributing to adverse brain health in lonely individuals. In this study, we …
Prenatal social support in low-risk pregnancy shapes placental epigenome
Background Poor social support during pregnancy has been linked to inflammation and
adverse pregnancy and childhood health outcomes. Placental epigenetic alterations may …
adverse pregnancy and childhood health outcomes. Placental epigenetic alterations may …