This review addresses key findings on loneliness from the social, neurobiological and
clinical fields. From a translational perspective, results from studies in humans and animals …

Major depression (MD) is a serious psychiatric illness afflicting nearly 5% of the world's
population. A large correlational literature suggests that loneliness is a prospective risk …

Background Several psychiatric disorders have been associated with increased risk of
cardiovascular disease (CVD), however, the role of familial factors and the main disease …

Cardiovascular diseases (CVDs) constitute one of the significant causes of death worldwide.
Different pathological states are linked to CVDs, which despite interventions and treatments …

Loneliness, or perceived social isolation, is a leading predictor of all-cause mortality and is
increasingly considered a public health epidemic afflicting significant portions of the general …

Background Immune mechanisms are indicated in schizophrenia (SCZ). Recent genome-
wide association studies (GWAS) have identified genetic variants associated with SCZ and …

Background Multiple observational studies have reported substantial comorbidity between
neuropsychiatric disorders and cardiovascular disease (CVD), but the underlying …

Patients with bipolar disorder (BIP) have a high risk of cardiovascular disease (CVD),
despite considerable individual variation. The mechanisms underlying comorbid CVD in BIP …

Introduction Loneliness is a negative experience arising from a mismatch between
perceived and actual social relationships. Several dimensions of loneliness have been …

Loneliness is linked to increased risk for Alzheimer's disease, but little is known about
factors potentially contributing to adverse brain health in lonely individuals. In this study, we …