Small and long non-coding RNAs: Past, present, and future
LL Chen, VN Kim - Cell, 2024 - cell.com
Since the introduction of the central dogma of molecular biology in 1958, various RNA
species have been discovered. Messenger RNAs transmit genetic instructions from DNA to …
species have been discovered. Messenger RNAs transmit genetic instructions from DNA to …
Genome annotation: From human genetics to biodiversity genomics
R Guigó - Cell Genomics, 2023 - cell.com
Within the next decade, the genomes of 1.8 million eukaryotic species will be sequenced.
Identifying genes in these sequences is essential to understand the biology of the species …
Identifying genes in these sequences is essential to understand the biology of the species …
The hidden impact of in-source fragmentation in metabolic and chemical mass spectrometry data interpretation
Mass spectrometry, specifically liquid chromatography–tandem mass spectrometry (LC–
MS/MS), stands at the forefront of metabolomic, pharmaceutical and clinical analyses …
MS/MS), stands at the forefront of metabolomic, pharmaceutical and clinical analyses …
Universal cell embeddings: A foundation model for cell biology
Develo** a universal representation of cells which encompasses the tremendous
molecular diversity of cell types within the human body and more generally, across species …
molecular diversity of cell types within the human body and more generally, across species …
CHESS 3: an improved, comprehensive catalog of human genes and transcripts based on large-scale expression data, phylogenetic analysis, and protein structure
CHESS 3 represents an improved human gene catalog based on nearly 10,000 RNA-seq
experiments across 54 body sites. It significantly improves current genome annotation by …
experiments across 54 body sites. It significantly improves current genome annotation by …
Natural antisense transcripts as versatile regulators of gene expression
Long non-coding RNAs (lncRNAs) are emerging as a major class of gene products that
have central roles in cell and developmental biology. Natural antisense transcripts (NATs) …
have central roles in cell and developmental biology. Natural antisense transcripts (NATs) …
[HTML][HTML] Functional roles of conserved lncRNAs and circRNAs in eukaryotes
J Li, X Wang - Non-coding RNA Research, 2024 - Elsevier
Long non-coding RNAs (lncRNAs) and circular RNAs (circRNAs) have emerged as critical
regulators in essentially all biological processes across eukaryotes. They exert their …
regulators in essentially all biological processes across eukaryotes. They exert their …
[HTML][HTML] Competing endogenous RNAs (ceRNAs) and drug resistance to cancer therapy
Competing endogenous RNAs (ceRNAs) are transcripts that possess highly similar
microRNA response elements (MREs). microRNAs (miRNAs) are short, endogenous, single …
microRNA response elements (MREs). microRNAs (miRNAs) are short, endogenous, single …
High‐throughput molecular assays for inclusion in personalised oncology trials–State‐of‐the‐art and beyond
A Edsjö, HG Russnes, J Lehtiö… - Journal of internal …, 2024 - Wiley Online Library
In the last decades, the development of high‐throughput molecular assays has
revolutionised cancer diagnostics, paving the way for the concept of personalised cancer …
revolutionised cancer diagnostics, paving the way for the concept of personalised cancer …
Application of smart-responsive hydrogels in nucleic acid and nucleic acid-based target sensing: A review
M Song, J Zhang, K Shen, Y Hu, W Shen… - Biosensors and …, 2024 - Elsevier
In recent years, nucleic acid-related sensing and detection have become essential in clinical
diagnostics, treatment and genoty**, especially in connection with the Human Genome …
diagnostics, treatment and genoty**, especially in connection with the Human Genome …