Pneumococcal meningitis continues to be associated with high rates of mortality and long-
term neurological sequelae. The most common route of infection starts by nasopharyngeal …

Proinflammatory cytokines and chemokines have been implicated in the pathogenesis of
several neurological and neurodegenerative disorders. Prominent among such factors is the …

Silver nanoparticles (AgNPs) have been used as an antimicrobial and disinfectant agents.
However, there is limited information about antitumor potential. Therefore, this study focused …

Background Streptococcus pneumoniae meningitis is a serious inflammatory disease of the
central nervous system (CNS) and is associated with high morbidity and mortality rates. The …

Tumor necrosis factor (TNF)-α has been reported to modulate brain injury, but remarkably,
little is known about its effects on neurogenesis. We report that TNF-α strongly influences …

The mechanism of acacetin-induced apoptosis of human breast cancer MCF-7 cells was
investigated. Acacetin caused 50% growth inhibition (IC 50) of MCF-7 cells at 26.4±0.7 μM …

Since the virtual eradication of meningitis due to Haemophilus influenzae type B by
vaccination in the developed world, pneumococcal meningitis has become the leading …

In an infant rat model of pneumococcal meningitis the effect of dexamethasone on neuronal
injury in the hippocampus and on learning disability after recovery from the disease was …

Metalloproteinases—such as matrix metalloproteinases (MMPs) and a disintegrin and
metalloproteinases (ADAMs)—are involved in various diseases of the nervous system but …

Background Pneumococcal meningitis is associated with high risk of neurological sequelae
such as cognitive impairment and hearing loss. These sequelae are due to parenchymal …