Dehydroamino acid residues in bioactive natural products
S Wang, K Wu, YJ Tang, H Deng - Natural Product Reports, 2024 - pubs.rsc.org
Covering: 2000 to up to 2023 α, β-Dehydroamino acids (dhAAs) are unsaturated
nonproteinogenic amino acids found in a wide array of naturally occurring peptidyl …
nonproteinogenic amino acids found in a wide array of naturally occurring peptidyl …
Exploring the diverse landscape of biaryl-containing peptides generated by cytochrome P450 macrocyclases
Cytochrome P450 enzymes (P450s) catalyze diverse oxidative cross-coupling reactions
between aromatic substrates in the natural product biosynthesis. Specifically, P450s install …
between aromatic substrates in the natural product biosynthesis. Specifically, P450s install …
Proteases involved in leader peptide removal during RiPP biosynthesis
SM Eslami, WA van der Donk - ACS Bio & Med Chem Au, 2023 - ACS Publications
Ribosomally synthesized and post-translationally modified peptides (RiPPs) have received
much attention in recent years because of their promising bioactivities and the portability of …
much attention in recent years because of their promising bioactivities and the portability of …
Bacterial Cytochrome P450 Catalyzed Post‐translational Macrocyclization of Ribosomal Peptides
Ribosomally synthesized and post‐translationally modified peptides (RiPPs) are a
fascinating group of natural products that exhibit diverse structural features and bioactivities …
fascinating group of natural products that exhibit diverse structural features and bioactivities …
An intramolecular macrocyclase in plant ribosomal peptide biosynthesis
The biosynthetic dogma of ribosomally synthesized and posttranslationally modified
peptides (RiPP) involves enzymatic intermolecular modification of core peptide motifs in …
peptides (RiPP) involves enzymatic intermolecular modification of core peptide motifs in …
Deciphering the ABA and GA biosynthesis approach of Bacillus pumilus, mechanistic approach, explaining the role of metabolic region as an aid in improving the …
Bacillus pumilus plays an essential role in agricultural applications as a beneficial microbe
and for sustainable agriculture production. However, the underlying mechanisms of B …
and for sustainable agriculture production. However, the underlying mechanisms of B …
Plant peptides–redefining an area of ribosomally synthesized and post-translationally modified peptides
Covering 1965 to February 2024Plants are prolific peptide chemists and are known to make
thousands of different peptidic molecules. These peptides vary dramatically in their size …
thousands of different peptidic molecules. These peptides vary dramatically in their size …
Functional and Promiscuity Studies of Three-Residue Cyclophane Forming Enzymes Show Nonnative C–C Cross-Linked Products and Leader-Dependent …
Enzymes catalyzing peptide macrocyclization are important biochemical tools in drug
discovery. The three-residue cy clophane-f orming e nzyme s (3-CyFEs) are an emerging …
discovery. The three-residue cy clophane-f orming e nzyme s (3-CyFEs) are an emerging …
Peptide crosslinking by a class of plant copper enzymes
BURP domain peptide cyclases, or BpCs (an abbreviation we recommend in this opinion),
are an emerging class of copper enzymes which catalyze the oxidative macrocyclization of …
are an emerging class of copper enzymes which catalyze the oxidative macrocyclization of …
Reassignment of the Structure of a Tryptophan‐Containing Cyclic Tripeptide Produced by the Biarylitide Crosslinking Cytochrome P450blt
The structure of the sidechain crosslinked Tyr‐Leu‐Trp peptide produced by the biarylitide
crosslinking cytochrome P450Blt from Micromonospora sp. MW‐13 has been reanalysed by …
crosslinking cytochrome P450Blt from Micromonospora sp. MW‐13 has been reanalysed by …