Metabolomics—the link between genotypes and phenotypes
O Fiehn - Functional genomics, 2002 - Springer
Metabolites are the end products of cellular regulatory processes, and their levels can be
regarded as the ultimate response of biological systems to genetic or environmental …
regarded as the ultimate response of biological systems to genetic or environmental …
Combining genomics, metabolome analysis, and biochemical modelling to understand metabolic networks
O Fiehn - Comparative and functional genomics, 2001 - Wiley Online Library
Now that complete genome sequences are available for a variety of organisms, the
elucidation of gene functions involved in metabolism necessarily includes a better …
elucidation of gene functions involved in metabolism necessarily includes a better …
COPASI—a complex pathway simulator
Motivation: Simulation and modeling is becoming a standard approach to understand
complex biochemical processes. Therefore, there is a big need for software tools that allow …
complex biochemical processes. Therefore, there is a big need for software tools that allow …
[图书][B] Systems biology: a textbook
This advanced textbook is tailored for an introductory course in Systems Biology and is well-
suited for biologists as well as engineers and computer scientists. It comes with student …
suited for biologists as well as engineers and computer scientists. It comes with student …
Genome-scale models of microbial cells: evaluating the consequences of constraints
Microbial cells operate under governing constraints that limit their range of possible
functions. With the availability of annotated genome sequences, it has become possible to …
functions. With the availability of annotated genome sequences, it has become possible to …
[图书][B] Systems biology: properties of reconstructed networks
BØ Palsson - 2006 - books.google.com
Genome sequences are now available that enable us to determine the biological
components that make up a cell or an organism. The discipline of systems biology examines …
components that make up a cell or an organism. The discipline of systems biology examines …
A general definition of metabolic pathways useful for systematic organization and analysis of complex metabolic networks
A set of linear pathways often does not capture the full range of behaviors of a metabolic
network. The concept of 'elementary flux modes' provides a mathematical tool to define and …
network. The concept of 'elementary flux modes' provides a mathematical tool to define and …
[图书][B] Analysis of biological networks
BH Junker, F Schreiber - 2008 - Wiley Online Library
Analysis of biological networks ANALYSIS OF BIOLOGICAL NETWORKS Page 2
ANALYSIS OF BIOLOGICAL NETWORKS EDITED BY BJO RN H. JUNKER and FALK …
ANALYSIS OF BIOLOGICAL NETWORKS EDITED BY BJO RN H. JUNKER and FALK …
Evolutionary programming as a platform for in silico metabolic engineering
Background Through genetic engineering it is possible to introduce targeted genetic
changes and hereby engineer the metabolism of microbial cells with the objective to obtain …
changes and hereby engineer the metabolism of microbial cells with the objective to obtain …
A methodology for the structural and functional analysis of signaling and regulatory networks
Background Structural analysis of cellular interaction networks contributes to a deeper
understanding of network-wide interdependencies, causal relationships, and basic …
understanding of network-wide interdependencies, causal relationships, and basic …