The cellular paradigm of chlamydial pathogenesis

RS Stephens - Trends in microbiology, 2003 - cell.com
Diseases caused by Chlamydia are based on intense and chronic inflammation elicited and
maintained by reinfection or persistent infection. The traditional view in the field is that …

Background and Current Knowledge of Chlamydia pneumoniae and Atherosclerosis

JT Grayston - The Journal of infectious diseases, 2000 - academic.oup.com
Attributes of Chlamydia pneumoniae of potential importance to a relationship with
atherosclerosis are described. Among these are that C. pneumoniae is not new. It is unique …

Recurrent chlamydial infections increase the risks of hospitalization for ectopic pregnancy and pelvic inflammatory disease

SD Hillis, LM Owens, PA Marchbanks… - American journal of …, 1997 - Elsevier
OBJECTIVE: We examined whether the risks of hospitalization for ectopic pregnancy and
pelvic inflammatory disease increase with increasing numbers of chlamydial infections …

Challenges of ophthalmic care in the develo** world

A Sommer, HR Taylor, TD Ravilla, S West… - JAMA …, 2014 - jamanetwork.com
Global blindness exacts an enormous financial and social cost on develo** countries.
Reducing the prevalence of blindness globally requires a set of strategies that are different …

Importance of reinfection in the pathogenesis of trachoma

JT Grayston, S Wang, L Yeh… - Reviews of infectious …, 1985 - academic.oup.com
The authors' epidemiologic studies of trachoma on Taiwan and experimental monkey eye
infections with and without Chlamydia trachomatis immunization are reviewed for the data …

Trachoma: Protective and Pathogenic Ocular Immune Responses to Chlamydia trachomatis

VH Hu, MJ Holland, MJ Burton - PLoS neglected tropical diseases, 2013 - journals.plos.org
Trachoma, caused by Chlamydia trachomatis (Ct), is the leading infectious blinding disease
worldwide. Chronic conjunctival inflammation develops in childhood and leads to eyelid …

Chlamydial disease pathogenesis. The 57-kD chlamydial hypersensitivity antigen is a stress response protein.

RP Morrison, RJ Belland, K Lyng… - The Journal of …, 1989 - rupress.org
Chlamydia trachomatis infection of humans is commonly a localized inflammation that can
result in infertility, blindness, and perhaps arthritis. The pathogenic process (es) that cause …

A live-attenuated chlamydial vaccine protects against trachoma in nonhuman primates

L Kari, WM Whitmire, N Olivares-Zavaleta… - Journal of Experimental …, 2011 - rupress.org
Blinding trachoma is an ancient neglected tropical disease caused by Chlamydia
trachomatis for which a vaccine is needed. We describe a live-attenuated vaccine that is …

Trachoma

HR Wright, A Turner, HR Taylor - The Lancet, 2008 - thelancet.com
Trachoma is a keratoconjunctivitis caused by ocular infection with Chlamydia trachomatis.
Repeated or persistent episodes lead to increasingly severe inflammation that can progress …

The simplified trachoma grading system, amended

AW Solomon, AB Kello, M Bangert… - Bulletin of the World …, 2020 - pmc.ncbi.nlm.nih.gov
A simplified grading system for trachoma was published by the World Health Organization
(WHO) in 1987. Intended for use by non-specialist personnel working at community level …