Transforming growth factor (TGF)-β is a multifunctional cytokine expressed by almost every
tissue and cell type. The signal transduction of TGF-β can stimulate diverse cellular …

The transforming growth factor beta (TGF‐β) family forms a group of three isoforms, TGF‐β1,
TGF‐β2, and TGF‐β3, with their structure formed by interrelated dimeric polypeptide chains …

Recent developments in sequencing techniques have enabled rapid and high-throughput
generation of sequence data, democratizing the ability to compile information on large …

Regeneration capacity declines with age, but why juvenile organisms show enhanced tissue
repair remains unexplained. Lin28a, a highly conserved RNA-binding protein expressed …

Significance: Transforming growth factor β (TGFβ) has a crucial role in maintaining skin
homeostasis. TGFβ signaling is important for re-epithelialization, inflammation …

Transforming growth factor beta (TGFβ) signalling is essential for wound healing, including
both non-specific scar formation and tissue-specific regeneration. Specific TGFβ isoforms …

The appearance and growth of malignant tumors is a complicated process that is regulated
by a number of genes. In recent years, studies have revealed that the transforming growth …

Tendon healing is characterized by the formation of fibrovascular scar tissue, as tendon has
very little intrinsic regenerative capacity. This creates a substantial clinical challenge in the …

Whereas amphibians regenerate lost appendages spontaneously, mammals generally form
scars over the injury site through the process of wound repair. The MRL mouse strain is an …

Significance: Wound healing is a complex physiological process involving a multitude of
growth factors, among which transforming growth factor beta (TGF-β) has the broadest …