Applications of focused ultrasound in the brain: from thermoablation to drug delivery
Focused ultrasound (FUS) is a disruptive medical technology, and its implementation in the
clinic represents the culmination of decades of research. Lying at the convergence of …
clinic represents the culmination of decades of research. Lying at the convergence of …
From gut microbiota to host appetite: gut microbiota-derived metabolites as key regulators
H Han, B Yi, R Zhong, M Wang, S Zhang, J Ma, Y Yin… - Microbiome, 2021 - Springer
Feelings of hunger and satiety are the key determinants for maintaining the life of humans
and animals. Disturbed appetite control may disrupt the metabolic health of the host and …
and animals. Disturbed appetite control may disrupt the metabolic health of the host and …
Applications of focused ultrasound-mediated blood-brain barrier opening
The blood brain barrier (BBB) plays a critically important role in the regulation of central
nervous system (CNS) homeostasis, but also represents a major limitation to treatments of …
nervous system (CNS) homeostasis, but also represents a major limitation to treatments of …
Ultrasound technologies for imaging and modulating neural activity
Visualizing and perturbing neural activity on a brain-wide scale in model animals and
humans is a major goal of neuroscience technology development. Established electrical and …
humans is a major goal of neuroscience technology development. Established electrical and …
BBB opening with focused ultrasound in nonhuman primates and Parkinson's disease patients: Targeted AAV vector delivery and PET imaging
Intracerebral vector delivery in nonhuman primates has been a major challenge. We report
successful blood-brain barrier opening and focal delivery of adeno-associated virus …
successful blood-brain barrier opening and focal delivery of adeno-associated virus …
[HTML][HTML] Transcranial focused ultrasound stimulation with high spatial resolution
Background Low-intensity transcranial focused ultrasound stimulation is a promising
candidate for noninvasive brain stimulation and accurate targeting of brain circuits because …
candidate for noninvasive brain stimulation and accurate targeting of brain circuits because …
[HTML][HTML] Combining brain perturbation and neuroimaging in non-human primates
Brain perturbation studies allow detailed causal inferences of behavioral and neural
processes. Because the combination of brain perturbation methods and neural …
processes. Because the combination of brain perturbation methods and neural …
[HTML][HTML] Role for caveolin-mediated transcytosis in facilitating transport of large cargoes into the brain via ultrasound
R Pandit, WK Koh, RKP Sullivan, T Palliyaguru… - Journal of Controlled …, 2020 - Elsevier
The blood-brain barrier (BBB) is a dynamic diffusional barrier regulating the molecular and
chemical flux between the blood and brain, thereby preserving cerebral homeostasis …
chemical flux between the blood and brain, thereby preserving cerebral homeostasis …
Neuronavigated repetitive transcranial ultrasound stimulation induces long-lasting and reversible effects on oculomotor performance in non-human primates
Since the late 2010s, Transcranial Ultrasound Stimulation (TUS) has been used
experimentally to carryout safe, non-invasive stimulation of the brain with better spatial …
experimentally to carryout safe, non-invasive stimulation of the brain with better spatial …
Lactobacillus Ameliorates SD-Induced Stress Responses and Gut Dysbiosis by Increasing the Absorption of Gut-Derived GABA in Rhesus Monkeys
N Zhao, Y Shu, C Jian, Z Zhou, H Bao, X Li… - Frontiers in …, 2022 - frontiersin.org
Sleep deprivation (SD) has become a health problem in the modern society. Although
probiotics supplementation has been proven to improve SD-induced gut dysbiosis, the …
probiotics supplementation has been proven to improve SD-induced gut dysbiosis, the …