A paradigm shift has recently occurred in the field of cancer therapeutics. Traditional
anticancer agents, such as chemotherapy, radiotherapy and small-molecule drugs targeting …

Abstract The Coronavirus Disease 2019 (COVID-19) pandemic is still spreading worldwide
over 2 years since its outbreak. The psychopathological implications in COVID-19 survivors …

Introducción: La pandemia por SARS-Cov-2 ha tenido un impacto negativo en múltiples
aspectos de la vida humana, tanto en lo físico, psicológico, económico, social y cultural. Las …

Cytokines regulate immune responses essential for maintaining immune homeostasis, as
deregulated cytokine signaling can lead to detrimental outcomes, including inflammatory …

Background There are many pharmacologic therapies that are being used or considered for
treatment of coronavirus disease 2019 (COVID-19). There is a need for frequently updated …

Introduction The recovery of other pathogens in patients with SARS-CoV-2 infection has
been reported, either at the time of a SARS-CoV-2 infection diagnosis (co-infection) or …

Objective To determine whether tocilizumab improves clinical outcomes for patients with
severe or critical coronavirus disease 2019 (covid-19). Design Randomised, open label trial …

Background The efficacy of interleukin-6 receptor blockade in hospitalized patients with
coronavirus disease 2019 (Covid-19) who are not receiving mechanical ventilation is …

Severe coronavirus disease 2019 (COVID-19) is characterized by systemic hyper-
inflammation, acute respiratory distress syndrome, and multiple organ failure. Cytokine …

Importance Therapies that improve survival in critically ill patients with coronavirus disease
2019 (COVID-19) are needed. Tocilizumab, a monoclonal antibody against the interleukin 6 …