Background Preventive therapy is a risk reduction option for women who have an increased
risk of breast cancer. The effectiveness of preventive therapy to reduce breast cancer …

Prevention of cancer remains the most promising strategy for reducing both its incidence
and the mortality due to this disease. For more than four decades, findings from …

Background Tamoxifen and raloxifene have limited patient acceptance for primary
prevention of breast cancer. Aromatase inhibitors prevent more contralateral breast cancers …

Abstract Background: The Surveillance, Epidemiology, and End Result (SEER) database
shows a variable increase in endometrial cancer incidence over time. The objective of this …

Importance Medications to reduce risk of breast cancer are effective for women at increased
risk but also cause adverse effects. Objective To update the 2013 US Preventive Services …

Two selective estrogen receptor modulators, tamoxifen and raloxifene, have been shown in
randomized clinical trials to reduce the risk of develo** primary invasive breast cancer in …

Tamoxifen is a selective oestrogen receptor modulator widely used for the treatment of
breast cancer. In addition to its activity as an oestrogen receptor agonist/antagonist …

While debate continues regarding short-term changes in breast cancer incidence and the
impact of screening on mortality, a long-term view of trends in incidence and mortality may …

Abstract BACKGROUND: For BRCA1/BRCA2 gene testing to benefit public health, mutation
carriers must initiate appropriate risk management strategies. There has been little research …

Chemotherapeutic drugs are primarily administered to cancer patients via oral or parenteral
routes. The use of transdermal drug delivery could potentially be a better alternative to …