Macrophage-targeted nanomedicine for the diagnosis and treatment of atherosclerosis
Nanotechnology could improve our understanding of the pathophysiology of atherosclerosis
and contribute to the development of novel diagnostic and therapeutic strategies to further …
and contribute to the development of novel diagnostic and therapeutic strategies to further …
Chemistry of MRI contrast agents: current challenges and new frontiers
Tens of millions of contrast-enhanced magnetic resonance imaging (MRI) exams are
performed annually around the world. The contrast agents, which improve diagnostic …
performed annually around the world. The contrast agents, which improve diagnostic …
Iron oxide nanoparticles: Diagnostic, therapeutic and theranostic applications
SM Dadfar, K Roemhild, NI Drude… - Advanced drug delivery …, 2019 - Elsevier
Many different iron oxide nanoparticles have been evaluated over the years, for a wide
variety of biomedical applications. We here summarize the synthesis, surface …
variety of biomedical applications. We here summarize the synthesis, surface …
Successful anti-PD-1 cancer immunotherapy requires T cell-dendritic cell crosstalk involving the cytokines IFN-γ and IL-12
Anti-PD-1 immune checkpoint blockers can induce sustained clinical responses in cancer
but how they function in vivo remains incompletely understood. Here, we combined intravital …
but how they function in vivo remains incompletely understood. Here, we combined intravital …
TLR7/8-agonist-loaded nanoparticles promote the polarization of tumour-associated macrophages to enhance cancer immunotherapy
Tumour-associated macrophages are abundant in many cancers, and often display an
immune-suppressive M2-like phenotype that fosters tumour growth and promotes resistance …
immune-suppressive M2-like phenotype that fosters tumour growth and promotes resistance …
DNA nanotechnology-enabled drug delivery systems
Over the past decade, we have seen rapid advances in applying nanotechnology in
biomedical areas including bioimaging, biodetection, and drug delivery. As an emerging …
biomedical areas including bioimaging, biodetection, and drug delivery. As an emerging …
[HTML][HTML] Manganese ferrite (MnFe2O4) nanostructures for cancer theranostics
Over the past decade, transition metal-based ferrite nanostructures, displaying MFe 2 O 4
stoichiometry (M 2+ cations, eg, Mn, Co, Ni and Zn), have been devised and examined …
stoichiometry (M 2+ cations, eg, Mn, Co, Ni and Zn), have been devised and examined …
Nanomaterials for in vivo imaging
In vivo imaging, which enables us to peer deeply within living subjects, is producing
tremendous opportunities both for clinical diagnostics and as a research tool. Contrast …
tremendous opportunities both for clinical diagnostics and as a research tool. Contrast …
Iron oxide nanoparticles inhibit tumour growth by inducing pro-inflammatory macrophage polarization in tumour tissues
Until now, the Food and Drug Administration (FDA)-approved iron supplement ferumoxytol
and other iron oxide nanoparticles have been used for treating iron deficiency, as contrast …
and other iron oxide nanoparticles have been used for treating iron deficiency, as contrast …
Targeted therapy in chronic diseases using nanomaterial-based drug delivery vehicles
The application of nanomedicines is increasing rapidly with the promise of targeted and
efficient drug delivery. Nanomedicines address the shortcomings of conventional therapy, as …
efficient drug delivery. Nanomedicines address the shortcomings of conventional therapy, as …