Hyperglycemia and oxidative stress: An integral, updated and critical overview of their metabolic interconnections
This review focuses on the multiple and reciprocal relationships that exist between oxidative
stress, hyperglycemia and diabetes and related metabolic disorders. Human metabolism …
stress, hyperglycemia and diabetes and related metabolic disorders. Human metabolism …
[HTML][HTML] Oxidative stress-based therapeutics in COPD
PJ Barnes - Redox biology, 2020 - Elsevier
Oxidative stress is a major driving mechanism in the pathogenesis of COPD. There is
increased oxidative stress in the lungs of COPD patients due to exogenous oxidants in …
increased oxidative stress in the lungs of COPD patients due to exogenous oxidants in …
The role of myeloperoxidase in biomolecule modification, chronic inflammation, and disease
Significance: The release of myeloperoxidase (MPO) by activated leukocytes is critical in
innate immune responses. MPO produces hypochlorous acid (HOCl) and other strong …
innate immune responses. MPO produces hypochlorous acid (HOCl) and other strong …
Antioxidant effects and mechanisms of medicinal plants and their bioactive compounds for the prevention and treatment of type 2 diabetes: an updated review
Diabetes mellitus is a metabolic disorder that majorly affects the endocrine gland, and it is
symbolized by hyperglycemia and glucose intolerance owing to deficient insulin secretory …
symbolized by hyperglycemia and glucose intolerance owing to deficient insulin secretory …
Hypochlorous acid chemistry in mammalian cells—influence on infection and role in various pathologies
CMC Andrés, JM Pérez de la Lastra, CA Juan… - International journal of …, 2022 - mdpi.com
This review discusses the formation of hypochlorous acid HOCl and the role of reactive
chlorinated species (RCS), which are catalysed by the enzyme myeloperoxidase MPO …
chlorinated species (RCS), which are catalysed by the enzyme myeloperoxidase MPO …
A review of the molecular mechanisms of hyperglycemia‐induced free radical generation leading to oxidative stress
The prevalence of diabetes is growing worldwide with an increasing morbidity and mortality
associated with the development of diabetes complications. Free radical production is a …
associated with the development of diabetes complications. Free radical production is a …
On the clinical pharmacology of reactive oxygen species
Reactive oxygen species (ROS) have been correlated with almost every human disease. Yet
clinical exploitation of these hypotheses by pharmacological modulation of ROS has been …
clinical exploitation of these hypotheses by pharmacological modulation of ROS has been …
Myeloperoxidase: Mechanisms, reactions and inhibition as a therapeutic strategy in inflammatory diseases
MJ Davies - Pharmacology & Therapeutics, 2021 - Elsevier
Heme peroxidases are a major source of reactive oxidants at sites of inflammation in
biological systems. The formation of some of these oxidants (eg hypochlorous acid, HOCl) is …
biological systems. The formation of some of these oxidants (eg hypochlorous acid, HOCl) is …
Molecularly imprinted plasmonic-based sensors for environmental contaminants—current state and future perspectives
The increase of production and consumption persistently introduce different pollutants into
the environment. The constant development and improvement of analytical methods for …
the environment. The constant development and improvement of analytical methods for …
Green Synthesis, Characterization, Antioxidant, Antibacterial and Enzyme Inhibition Effects of Chestnut (Castanea sativa) Honey-Mediated Silver Nanoparticles
In this study, chestnut honey-based silver nanoparticles (CH-AgNPs) were synthesized at
different temperatures (30, 60 and 90° C) and these nanoparticles were characterized by …
different temperatures (30, 60 and 90° C) and these nanoparticles were characterized by …