As long-term pool feeders, ticks have developed myriad strategies to remain discreetly but
solidly attached to their hosts for the duration of their blood meal. The critical biological …

Kunitz domain-containing proteins are ubiquitous serine protease inhibitors with promising
therapeutic potential. They target key proteases involved in major cellular processes such as …

Tick sialome is comprised of a rich cocktail of bioactive molecules that function as a tool to
disarm host immunity, assist blood-feeding, and play a vibrant role in pathogen …

New tick and tick-borne pathogen control approaches that are both environmentally
sustainable and which provide broad protection are urgently needed. Their development …

Ticks are obligate hematophagous parasites and are important vectors of a wide variety of
pathogens. These pathogens include spirochetes in the genus Borrelia that cause Lyme …

Ticks are obligatory blood-feeding ectoparasites, causing blood loss and skin damage in
their hosts. In addition, ticks also transmit a number of various pathogenic microorganisms …

Ticks must durably suppress vertebrate host responses (hemostasis, inflammation,
immunity) to avoid rejection and act as vectors of many pathogenic microorganisms that …

Recent studies have revealed that the coagulation system plays a role in mammalian innate
defense by entrap** bacteria in clots and generating antibacterial peptides. So, it is very …

Amblyomma sculptum is the main tick associated with human bites in Brazil and the main
vector of Rickettsia rickettsii, the causative agent of the most severe form of Brazilian spotted …

Protease inhibitors (PIs) are ubiquitous regulatory proteins present in all kingdoms. They
play crucial tasks in controlling biological processes directed by proteases which, if not …