From ancient herb to modern drug: Artemisia annua and artemisinin for cancer therapy
T Efferth - Seminars in cancer biology, 2017 - Elsevier
Artemisia annua L. is used throughout Asia and Africa as tea and press juice to treat malaria
and related symptomes (fever, chills). Its active ingredient, artemisinin (ARS), has been …
and related symptomes (fever, chills). Its active ingredient, artemisinin (ARS), has been …
[HTML][HTML] Development of nanoscale drug delivery systems of dihydroartemisinin for cancer therapy: A review
Abstract Dihydroartemisinin (DHA), a first-line antimalarial drug, has demonstrated great
anticancer effects in many types of tumors, including liver cancer, glioblastoma, and …
anticancer effects in many types of tumors, including liver cancer, glioblastoma, and …
Dihydroartemisinin inhibits the proliferation, colony formation and induces ferroptosis of lung cancer cells by inhibiting PRIM2/SLC7A11 axis
B Yuan, F Liao, ZZ Shi, Y Ren, XL Deng… - OncoTargets and …, 2020 - Taylor & Francis
Objective Lung cancer is the first leading cause of cancer-related deaths both worldwide
and in China and threatens human health and quality of life. New drugs and therapeutic …
and in China and threatens human health and quality of life. New drugs and therapeutic …
Artesunate induces autophagy dependent apoptosis through upregulating ROS and activating AMPK-mTOR-ULK1 axis in human bladder cancer cells
X Zhou, Y Chen, F Wang, H Wu, Y Zhang, J Liu… - Chemico-Biological …, 2020 - Elsevier
Artesunate is a kind of derivative of artemisinin, which possesses potent anti-cancer effect in
addition to its anti-malarial property. And autophagy was a highly conserved process …
addition to its anti-malarial property. And autophagy was a highly conserved process …
Artemisinin-type drugs for the treatment of hematological malignancies
Qinghaosu, known as artemisinin (ARS), has been for over two millennia, one of the most
common herbs prescribed in traditional Chinese medicine (TCM). ARS was developed as …
common herbs prescribed in traditional Chinese medicine (TCM). ARS was developed as …
Cancer combination therapies with artemisinin-type drugs
T Efferth - Biochemical pharmacology, 2017 - Elsevier
Artemisia annua L. is a Chinese medicinal plant, which is used throughout Asia and Africa
as tea or press juice to treat malaria. The bioactivity of its chemical constituent, artemisinin is …
as tea or press juice to treat malaria. The bioactivity of its chemical constituent, artemisinin is …
Recent pharmacological advances in the repurposing of artemisinin drugs
Artemisinins are a family of sesquiterpene lactones originally derived from the sweet
wormwood (Artemisia annua). Beyond their well‐characterized role as frontline antimalarial …
wormwood (Artemisia annua). Beyond their well‐characterized role as frontline antimalarial …
Artemisinin and its derivatives: A potential treatment for leukemia
Artemisinin (ART) and its derivatives are one of the most important classes of antimalarial
agents, originally derived from a Chinese medicinal plant called Artemisia annua L. Beyond …
agents, originally derived from a Chinese medicinal plant called Artemisia annua L. Beyond …
Artemisinin–second career as anticancer drug?
T Efferth - World Journal of Traditional Chinese Medicine, 2015 - journals.lww.com
Artemisinin represents a showcase example not only for the activity of medicinal herbs
deriving from traditional chinese medicine, but for phytotherapy in general. Its isolation from …
deriving from traditional chinese medicine, but for phytotherapy in general. Its isolation from …
Dihydroartemisinin increases gemcitabine therapeutic efficacy in ovarian cancer by inducing reactive oxygen species
Ovarian cancer is the major cause of death in women gynecological malignancy and
gemcitabine (GEM) is commonly used in related chemotherapy. However, more than 90 …
gemcitabine (GEM) is commonly used in related chemotherapy. However, more than 90 …