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miRNAs and androgen deprivation therapy for prostate cancer
MY Konoshenko, OE Bryzgunova… - Biochimica et Biophysica …, 2021 - Elsevier
Androgen deprivation therapy (ADT) is mainly used for the treatment of advanced, metastatic
or recurrent prostate cancer (PCa). However, patients progress to ADT resistance and …
or recurrent prostate cancer (PCa). However, patients progress to ADT resistance and …
Function of miRNA-145–5p in the pathogenesis of human disorders
S Kadkhoda, S Ghafouri-Fard - Pathology-Research and Practice, 2022 - Elsevier
Abstract miR-145–5p is a microRNA whose role in diverse disorders has been verified. This
miRNA is encoded by MIR145 gene on chromosome 5. This miRNA is mainly considered as …
miRNA is encoded by MIR145 gene on chromosome 5. This miRNA is mainly considered as …
NCAPG promotes the proliferation of hepatocellular carcinoma through PI3K/AKT signaling
C Gong, J Ai, Y Fan, J Gao, W Liu, Q Feng… - OncoTargets and …, 2019 - Taylor & Francis
Purpose Studies show that high expression of non-SMC condensin I complex subunit G
(NCAPG) is associated with many tumors. In this study, we explore the mechanism by which …
(NCAPG) is associated with many tumors. In this study, we explore the mechanism by which …
Regulation of antitumor miR‐144‐5p targets oncogenes: direct regulation of syndecan‐3 and its clinical significance
Y Yamada, T Arai, S Kojima, S Sugawara… - Cancer …, 2018 - Wiley Online Library
In the human genome, miR‐451a, miR‐144‐5p (passenger strand), and miR‐144‐3p (guide
strand) reside in clustered microRNA (mi RNA) sequences located within the 17q11. 2 …
strand) reside in clustered microRNA (mi RNA) sequences located within the 17q11. 2 …
RNA‐sequence‐based microRNA expression signature in breast cancer: tumor‐suppressive miR‐101‐5p regulates molecular pathogenesis
H Toda, N Seki, S Kurozumi, Y Shinden… - Molecular …, 2020 - Wiley Online Library
Aberrantly expressed microRNA (miRNA) are known to disrupt intracellular RNA networks in
cancer cells. Exploring miRNA‐dependent molecular networks is a major challenge in …
cancer cells. Exploring miRNA‐dependent molecular networks is a major challenge in …
NCAPG facilitates colorectal cancer cell proliferation, migration, invasion and epithelial–mesenchymal transition by activating the Wnt/β-catenin signaling pathway
Y Shi, C Ge, D Fang, W Wei, L Li, Q Wei, H Yu - Cancer cell international, 2022 - Springer
Background The condensation complex gene non-SMC condensin I complex subunit G
(NCAPG), a cell cycle-associated condensin, is over-expressed in various cancers …
(NCAPG), a cell cycle-associated condensin, is over-expressed in various cancers …
Regulation of NCAPG by miR‐99a‐3p (passenger strand) inhibits cancer cell aggressiveness and is involved in CRPC
T Arai, A Okato, Y Yamada, S Sugawara… - Cancer …, 2018 - Wiley Online Library
Effective treatments for patients with castration‐resistant prostate cancer (CRPC) have not
yet been established. Novel approaches for identification of putative therapeutic targets for …
yet been established. Novel approaches for identification of putative therapeutic targets for …
[HTML][HTML] Involvement of Dual Strands of miR-143 (miR-143-5p and miR-143-3p) and Their Target Oncogenes in the Molecular Pathogenesis of Lung …
H Sanada, N Seki, K Mizuno, S Misono… - International journal of …, 2019 - mdpi.com
Our analyses of tumor-suppressive microRNAs (miRNAs) and their target oncogenes have
identified novel molecular networks in lung adenocarcinoma (LUAD). Moreover, our recent …
identified novel molecular networks in lung adenocarcinoma (LUAD). Moreover, our recent …
Role and mechanism of NCAPD3 in promoting malignant behaviors in gastric cancer
SY Zhang, Q Luo, LR **ao, F Yang, J Zhu… - Frontiers in …, 2024 - frontiersin.org
Background: Gastric cancer (GC) is one of the major malignancies threatening human lives
and health. Non-SMC condensin II complex subunit D3 (NCAPD3) plays a crucial role in the …
and health. Non-SMC condensin II complex subunit D3 (NCAPD3) plays a crucial role in the …
Antitumor miR-150-5p and miR-150-3p inhibit cancer cell aggressiveness by targeting SPOCK1 in head and neck squamous cell carcinoma
K Koshizuka, T Hanazawa, N Kikkawa, K Katada… - Auris Nasus …, 2018 - Elsevier
Objective Our recent studies have revealed that both strands of pre-miRNAs, the guide
strand and the passenger strand, are involved in cancer pathogenesis. Analyses of miRNA …
strand and the passenger strand, are involved in cancer pathogenesis. Analyses of miRNA …