Ventricular arrhythmias in ischemic cardiomyopathy—New avenues for mechanism-guided treatment
M Amoni, E Dries, S Ingelaere, D Vermoortele… - Cells, 2021 - mdpi.com
Ischemic heart disease is the most common cause of lethal ventricular arrhythmias and
sudden cardiac death (SCD). In patients who are at high risk after myocardial infarction …
sudden cardiac death (SCD). In patients who are at high risk after myocardial infarction …
Creation and application of virtual patient cohorts of heart models
Patient-specific cardiac models are now being used to guide therapies. The increased use
of patient-specific cardiac simulations in clinical care will give rise to the development of …
of patient-specific cardiac simulations in clinical care will give rise to the development of …
Evaluating computational efforts and physiological resolution of mathematical models of cardiac tissue
Computational techniques have significantly advanced our understanding of cardiac
electrophysiology, yet they have predominantly concentrated on averaged models that do …
electrophysiology, yet they have predominantly concentrated on averaged models that do …
The association of cannabis use and cardiac dysrhythmias: a systematic review
JR Richards, E Blohm, KA Toles, AF Jarman… - Clinical …, 2020 - Taylor & Francis
Introduction: Cannabis use results in elevation of heart rate and blood pressure immediately
after use, primarily due to sympathetic nervous system stimulation and parasympathetic …
after use, primarily due to sympathetic nervous system stimulation and parasympathetic …
Uncertainty quantification and sensitivity analysis of left ventricular function during the full cardiac cycle
Patient-specific computer simulations can be a powerful tool in clinical applications, hel**
in diagnostics and the development of new treatments. However, its practical use depends …
in diagnostics and the development of new treatments. However, its practical use depends …
An audit of uncertainty in multi-scale cardiac electrophysiology models
Models of electrical activation and recovery in cardiac cells and tissue have become
valuable research tools, and are beginning to be used in safety-critical applications …
valuable research tools, and are beginning to be used in safety-critical applications …
A smoothed boundary bidomain model for cardiac simulations in anatomically detailed geometries
This manuscript presents a novel finite difference method to solve cardiac bidomain
equations in anatomical models of the heart. The proposed method employs a smoothed …
equations in anatomical models of the heart. The proposed method employs a smoothed …
Factors promoting conduction slowing as substrates for block and reentry in infarcted hearts
The development of effective and safe therapies for scar-related ventricular tachycardias
requires a detailed understanding of the mechanisms underlying the conduction block that …
requires a detailed understanding of the mechanisms underlying the conduction block that …
[HTML][HTML] Complex-order fractional diffusion in reaction-diffusion systems
Fractional differential equations have become a fundamental modelling approach for
understanding and simulating the many aspects of non-locality and spatial heterogeneity of …
understanding and simulating the many aspects of non-locality and spatial heterogeneity of …
A 3D transmurally heterogeneous computational model of the Brugada Syndrome phenotype
In this work, we present a computational study of the Brugada Syndrome (BrS) phenotype
aimed at investigating the main factors contributing to the development of arrhythmias. We …
aimed at investigating the main factors contributing to the development of arrhythmias. We …