Anxiety disorders are a significant problem in the community, and recent neuroimaging
research has focused on determining the brain circuits that underlie them. Research on the …

Neuroimaging studies report evidence for two distinct pathophysiological models of
obsessive-compulsive disorder (OCD): disrupted fronto-striatal circuits and impaired large …

Obsessive-compulsive disorder is a severe and disabling clinical condition that usually
arises in late adolescence or early adulthood and, if left untreated, has a chronic course …

Behavioral state is known to influence interactions between thalamus and cortex, which are
important for sensation, action, and cognition. The thalamic reticular nucleus (TRN) is …

For the neurobiologist, key observations about these There is no known overt locus of
neuronal degeneration symptoms include the following: in OCD as there is, for example, in …

Recent neurobiological models of obsessive–compulsive disorder (OCD) posit that a
dysfunction in orbitofrontal–subcortical circuitry underlies the etiology of this disorder. Much …

Neuroimaging research has helped to advance neurobiological models of anxiety disorders.
The amygdala is known to play an important role in normal fear conditioning and is …

Functional imaging studies have reported with remarkable consistency hyperactivity in the
orbitofrontal cortex (OFC), anterior cingulate cortex (ACC), and caudate nucleus of patients …

Obsessive–compulsive disorder (OCD) is characterized by repetitive intrusive thoughts and
compulsive time-consuming behaviors classified into three to five distinct symptom …

Greenfield's Neuropathology, the world's leading neuropathology reference, provides a
comprehensive account of the pathological findings in neurological disease, their biological …