The multifaceted role of the ventromedial prefrontal cortex in emotion, decision making, social cognition, and psychopathology

J Hiser, M Koenigs - Biological psychiatry, 2018 - Elsevier
The ventromedial prefrontal cortex (vmPFC) has been implicated in a variety of social,
cognitive, and affective functions that are commonly disrupted in mental illness. In this …

The neurobiology of drug addiction: cross-species insights into the dysfunction and recovery of the prefrontal cortex

AO Ceceli, CW Bradberry, RZ Goldstein - Neuropsychopharmacology, 2022 - nature.com
A growing preclinical and clinical body of work on the effects of chronic drug use and drug
addiction has extended the scope of inquiry from the putative reward-related subcortical …

The role of dorsolateral and ventromedial prefrontal cortex in the processing of emotional dimensions

V Nejati, R Majdi, MA Salehinejad, MA Nitsche - Scientific reports, 2021 - nature.com
The ventromedial and dorsolateral prefrontal cortex are two major prefrontal regions that
usually interact in serving different cognitive functions. On the other hand, these regions are …

Lesion studies in contemporary neuroscience

AR Vaidya, MS Pujara, M Petrides, EA Murray… - Trends in cognitive …, 2019 - cell.com
Studies of humans with focal brain damage and non-human animals with experimentally
induced brain lesions have provided pivotal insights into the neural basis of behavior. As the …

Impulse control and related disorders in Parkinson's disease

D Weintraub, DO Claassen - International review of neurobiology, 2017 - Elsevier
Impulse control disorders (ICDs), such as compulsive gambling, buying, sexual, and eating
behaviors, are a serious and increasingly recognized complication in Parkinson's disease …

Love is analogous to money in human brain: Coordinate-based and functional connectivity meta-analyses of social and monetary reward anticipation

R Gu, W Huang, J Camilleri, P Xu, P Wei… - Neuroscience & …, 2019 - Elsevier
Both social and material rewards play a crucial role in daily life and function as strong
incentives for various goal-directed behaviors. However, it remains unclear whether the …

Human ventromedial prefrontal cortex is necessary for prosocial motivation

PL Lockwood, J Cutler, D Drew, A Abdurahman… - Nature Human …, 2024 - nature.com
Ventromedial prefrontal cortex (vmPFC) is vital for decision-making. Functional
neuroimaging links vmPFC to processing rewards and effort, while parallel work suggests …

Reward sensitivity deficits modulated by dopamine are associated with apathy in Parkinson's disease

K Muhammed, S Manohar, M Ben Yehuda, TTJ Chong… - Brain, 2016 - academic.oup.com
Apathy is a debilitating and under-recognized condition that has a significant impact in many
neurodegenerative disorders. In Parkinson's disease, it is now known to contribute to worse …

Large-scale lesion symptom map** of depression identifies brain regions for risk and resilience

NT Trapp, JE Bruss, K Manzel, J Grafman, D Tranel… - Brain, 2023 - academic.oup.com
Understanding neural circuits that support mood is a central goal of affective neuroscience,
and improved understanding of the anatomy could inform more targeted interventions in …

Modulating musical reward sensitivity up and down with transcranial magnetic stimulation

E Mas-Herrero, A Dagher, RJ Zatorre - Nature human behaviour, 2018 - nature.com
Humans have the unique capacity to experience pleasure from aesthetic stimuli, such as art
and music. Recent neuroimaging findings with music have led to a model in which …