Silk chemistry and biomedical material designs

JK Sahoo, O Hasturk, T Falcucci… - Nature Reviews Chemistry, 2023 - nature.com
Silk fibroin has applications in different medical fields such as tissue engineering,
regenerative medicine, drug delivery and medical devices. Advances in silk chemistry and …

The biomedical use of silk: past, present, future

C Holland, K Numata… - Advanced healthcare …, 2019 - Wiley Online Library
Humans have long appreciated silk for its lustrous appeal and remarkable physical
properties, yet as the mysteries of silk are unraveled, it becomes clear that this outstanding …

Designing scaffolds for corneal regeneration

M Ahearne, J Fernández‐Pérez… - Advanced Functional …, 2020 - Wiley Online Library
Corneal blindness is one of the most common causes of vision loss worldwide, affecting
millions of people. To treat these patients, researchers have been examining different …

3D bioprinting using UNIversal orthogonal network (UNION) bioinks

SM Hull, CD Lindsay, LG Brunel… - Advanced Functional …, 2021 - Wiley Online Library
Abstract Three‐dimensional (3D) bioprinting is a promising technology to produce tissue‐
like structures, but a lack of diversity in bioinks is a major limitation. Ideally each cell type …

Wound-healing studies in cornea and skin: parallels, differences and opportunities

A Bukowiecki, D Hos, C Cursiefen… - International journal of …, 2017 - mdpi.com
The cornea and the skin are both organs that provide the outer barrier of the body. Both
tissues have developed intrinsic mechanisms that protect the organism from a wide range of …

Corneal tissue engineering: recent advances and future perspectives

CE Ghezzi, J Rnjak-Kovacina… - Tissue Engineering Part B …, 2015 - liebertpub.com
To address the growing need for corneal transplants two main approaches are being
pursued: allogenic and synthetic materials. Allogenic tissue from human donors is currently …

Characterization of cornea-specific bioink: high transparency, improved in vivo safety

H Kim, MN Park, J Kim, J Jang… - Journal of tissue …, 2019 - journals.sagepub.com
Corneal transplantation is a typical surgical procedure for severe corneal diseases.
However, the waiting time for a donor cornea has gradually increased due to a decrease in …

Mechanical properties of bioengineered corneal stroma

N Formisano, C van der Putten, R Grant… - Advanced …, 2021 - Wiley Online Library
For the majority of patients with severe corneal injury or disease, corneal transplantation is
the only suitable treatment option. Unfortunately, the demand for donor corneas greatly …

[HTML][HTML] Corneal regeneration: A review of stromal replacements

S Matthyssen, B Van den Bogerd, SN Dhubhghaill… - Acta biomaterialia, 2018 - Elsevier
Corneal blindness is traditionally treated by transplantation of a donor cornea, or in severe
cases by implantation of an artificial cornea or keratoprosthesis. Due to severe donor …

In vitro 3D corneal tissue model with epithelium, stroma, and innervation

S Wang, CE Ghezzi, R Gomes, RE Pollard… - Biomaterials, 2017 - Elsevier
The interactions between corneal nerve, epithelium, and stroma are essential for
maintaining a healthy cornea. Thus, corneal tissue models that more fully mimic the …