Mesenchymal stem cells empowering tendon regenerative therapies
Tendon tissues have limited healing capacity. The incidence of tendon injuries and the
unsatisfactory functional outcomes of tendon repair are driving the search for alternative …
unsatisfactory functional outcomes of tendon repair are driving the search for alternative …
Progress in cell-based therapies for tendon repair
The last decade has seen significant developments in cell therapies, based on permanently
differentiated, reprogrammed or engineered stem cells, for tendon injuries and degenerative …
differentiated, reprogrammed or engineered stem cells, for tendon injuries and degenerative …
Living nanofiber yarn-based woven biotextiles for tendon tissue engineering using cell tri-culture and mechanical stimulation
Non-woven nanofibrous scaffolds have been developed for tendon graft application by
using electrospinning strategies. However, electrospun nanofibrous scaffolds face some …
using electrospinning strategies. However, electrospun nanofibrous scaffolds face some …
In vitro innovation of tendon tissue engineering strategies
MR Citeroni, MC Ciardulli, V Russo… - International journal of …, 2020 - mdpi.com
Tendinopathy is the term used to refer to tendon disorders. Spontaneous adult tendon
healing results in scar tissue formation and fibrosis with suboptimal biomechanical …
healing results in scar tissue formation and fibrosis with suboptimal biomechanical …
Tendon-derived stem cells (TDSCs): from basic science to potential roles in tendon pathology and tissue engineering applications
PPY Lui, KM Chan - Stem cell reviews and reports, 2011 - Springer
Traditionally, tendons are considered to only contain tenocytes that are responsible for the
maintenance, repair and remodeling of tendons. Stem cells, which are termed tendon …
maintenance, repair and remodeling of tendons. Stem cells, which are termed tendon …
Effect of scaffold morphology and cell co-culture on tenogenic differentiation of HADMSC on centrifugal melt electrospun poly (L‑lactic acid) fibrous meshes
Engineered tendon grafts offer a promising alternative for grafting during the reconstruction
of complex tendon tears. The tissue-engineered tendon substitutes have the advantage of …
of complex tendon tears. The tissue-engineered tendon substitutes have the advantage of …
Biochemical and biomechanical gradients for directed bone marrow stromal cell differentiation toward tendon and bone
RI Sharma, JG Snedeker - Biomaterials, 2010 - Elsevier
Substrates with mechanical property gradients and various extracellular matrix ligand
loadings were evaluated for their ability to direct bone marrow stromal cell differentiation …
loadings were evaluated for their ability to direct bone marrow stromal cell differentiation …
[HTML][HTML] Advanced robotics to address the translational gap in tendon engineering
IL Sander, N Dvorak, JA Stebbins, AJ Carr… - Cyborg and Bionic …, 2022 - spj.science.org
Tendon disease is a significant and growing burden to healthcare systems. One strategy to
address this challenge is tissue engineering. A widely held view in this field is that …
address this challenge is tissue engineering. A widely held view in this field is that …
Progress with stem cell therapies for tendon tissue regeneration
F Migliorini, M Tingart, N Maffulli - Expert opinion on biological …, 2020 - Taylor & Francis
Introduction Chronic musculoskeletal pain is very prevalent, and accounts for major health-
care expenses. Many of the present therapeutic modalities are only partially effective, and …
care expenses. Many of the present therapeutic modalities are only partially effective, and …
ADSC-based cell therapies for musculoskeletal disorders: a review of recent clinical trials
Recently published clinical trials involving the use of adipose-derived stem cells (ADSCs)
indicated that approximately one-third of the studies were conducted on musculoskeletal …
indicated that approximately one-third of the studies were conducted on musculoskeletal …