Neuronal nicotinic acetylcholine receptors (nAChRs) belong to a super-family of Cysloop
ligand-gated ion channels that respond to endogenous acetylcholine (ACh) or other …

Nicotinic acetylcholine receptors (nAChRs) are widely distributed throughout the central
nervous system, being expressed in neurons and non-neuronal cells, where they participate …

The nicotinic acetylcholine receptor (nAChR) belongs to a superfamily of pentameric ligand-
gated ion channels involved in many physiologic and pathologic processes. Among …

The clinical development of selective alpha-7 nicotinic acetylcholine receptor (α7 nAChR)
agonists has hitherto been focused on disorders characterized by cognitive deficits (eg …

The α7-type nicotinic acetylcholine receptor is one of the most unique and interesting of all
the members of the cys-loop superfamily of ligand-gated ion channels. Since it was first …

Pentameric ligand‐gated ion channels (pLGICs) mediate fast neurotransmission in the
nervous system. Their dysfunction is associated with psychiatric, neurological and …

Nicotinic acetylcholine receptors (nAChRs) are receptors for the neurotransmitter
acetylcholine and are members of the 'Cys-loop'family of pentameric ligand-gated ion …

Traumatic brain injury (TBI) results in varying degrees of disability in a significant number of
persons annually. The mechanisms of cognitive dysfunction after TBI have been explored in …

In the central nervous system, deficits in cholinergic neurotransmission correlate with
decreased attention and cognitive impairment, while stimulation of neuronal nicotinic …

Background and Purpose—Temporary immunosuppression has been identified as a major
risk factor for the development of pneumonia after acute central nervous system injury …