The tuberculous granuloma and preexisting immunity
Pulmonary granulomas are widely considered the epicenters of the immune response to
Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB). Recent animal …
Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB). Recent animal …
Infections due to dysregulated immunity: an emerging complication of cancer immunotherapy
Immune checkpoint inhibitors (ICIs) have revolutionised cancer treatment. However, immune-
related adverse events (irAEs) are a common side effect which can mimic infection …
related adverse events (irAEs) are a common side effect which can mimic infection …
[HTML][HTML] TGFβ restricts expansion, survival, and function of T cells within the tuberculous granuloma
CD4 T cell effector function is required for optimal containment of Mycobacterium
tuberculosis (Mtb) infection. IFNɣ produced by CD4 T cells is a key cytokine that contributes …
tuberculosis (Mtb) infection. IFNɣ produced by CD4 T cells is a key cytokine that contributes …
Increased tuberculosis incidence due to immunotherapy based on PD-1 and PD-L1 blockade: A systematic review and meta-analysis
K Liu, D Wang, C Yao, M Qiao, Q Li, W Ren… - Frontiers in …, 2022 - frontiersin.org
Objectives In this study, we conducted a systematic review to determine tuberculosis (TB)
incidence due to immunotherapy with programmed cell death protein-1 (PD-1)/PD ligand …
incidence due to immunotherapy with programmed cell death protein-1 (PD-1)/PD ligand …
Dual nature of relationship between mycobacteria and cancer
M Fol, P Koziński, J Kulesza, P Białecki… - International Journal of …, 2021 - mdpi.com
Although the therapeutic effect of mycobacteria as antitumor agents has been known for
decades, recent epidemiological and experimental studies have revealed that …
decades, recent epidemiological and experimental studies have revealed that …
Lower IL-7 receptor expression of monocytes impairs antimycobacterial effector functions in patients with tuberculosis
Altered monocyte differentiation and effector functions characterize immune pathogenesis of
tuberculosis. IL-7 is an important factor for proliferation of T cells and impaired IL-7 sensitivity …
tuberculosis. IL-7 is an important factor for proliferation of T cells and impaired IL-7 sensitivity …
[HTML][HTML] Advances in molecular mechanisms of interaction between Mycobacterium tuberculosis and lung cancer: a narrative review
K **ong, W Sun, Y He, L Fan - Translational Lung Cancer …, 2021 - ncbi.nlm.nih.gov
Objective We systematically review the molecular mechanism of the interaction between
lung cancer (LC) and tuberculosis (TB), and put forward the existing problems in order to …
lung cancer (LC) and tuberculosis (TB), and put forward the existing problems in order to …
Tuberculosis infection following immune checkpoint inhibitor treatment for advanced cancer: a case report and literature review
C Lin, G Xu, S Gao, T Feng, S Li - Frontiers in Immunology, 2023 - frontiersin.org
Objective To investigate the clinical features of active tuberculosis (TB) infection due to
immune checkpoint inhibitors (ICIs) treatment in patients with advanced cancer. Methods We …
immune checkpoint inhibitors (ICIs) treatment in patients with advanced cancer. Methods We …
[HTML][HTML] The safety and efficacy of immunotherapy with anti-programmed cell death 1 monoclonal antibody for lung cancer complicated with Mycobacterium …
J Shi, J Li, Q Wang, X Cheng, H Du, R Han… - Translational Lung …, 2021 - ncbi.nlm.nih.gov
Background Anti-programmed cell death 1 (PD-1)/programmed cell death-ligand 1 (PD-L1)
immunotherapy has boosted the prognosis in advanced lung cancer. Meanwhile …
immunotherapy has boosted the prognosis in advanced lung cancer. Meanwhile …
Pulmonary tuberculosis associated with immune checkpoint inhibitors: a pharmacovigilance study
J Zhu, Z He, D Liang, X Yu, K Qiu, J Wu - Thorax, 2022 - thorax.bmj.com
We examined case reports of immune checkpoint inhibitors (ICIs) associated pulmonary
tuberculosis (PT) using data from the Food and Drug Administration Adverse Event …
tuberculosis (PT) using data from the Food and Drug Administration Adverse Event …