Acetylcholinesterase inhibitors (ChEI) are the global standard of care for the symptomatic
treatment of Alzheimer's disease (AD) and show significant positive effects in …

Cholinergic degeneration is significant in Lewy body disease, including Parkinson's
disease, dementia with Lewy bodies, and isolated REM sleep behavior disorder. Extensive …

INTRODUCTION Degeneration of cortical cholinergic projections from the nucleus basalis of
Meynert (NBM) is characteristic of dementia with Lewy bodies (DLB) and Alzheimer's …

We evaluated alterations in the nucleus basalis of Meynert (NBM) volume and integrity of
cholinergic white matter pathways in objective subtle cognitive impairment (Obj-SCI) …

Background Subjective cognitive decline (SCD) is a risk factor for future cognitive
impairment and dementia. It is uncertain whether the neurodegeneration of the cholinergic …

Cortical cholinergic projections originate from subregions of the basal forebrain (BF). To
examine its organization in humans, we computed multimodal gradients of BF connectivity …

Background Numerous neuroimaging studies have reported that Alzheimer's disease (AD)
spectrum have been linked to alterations in intrinsic functional activity and cortical thickness …

Aim Scutellaria baicalensis, a traditional Chinese medicinal herb renowned for its anti-
inflammatory, antioxidant, and anti-tumor properties, has shown promise in alleviating …

Abstract Dementia, particularly Alzheimer's Disease (AD), has links to modifiable risk factors,
particularly physical inactivity. However, cognitive benefits are generally attributed to aerobic …

Introduction It is unclear how rates of white matter microstructural decline differ between
normal aging and abnormal aging. Methods Diffusion MRI data from several well …