In individuals with sensory-motor impairments, missing limb functions can be restored using
neuroprosthetic devices that directly interface with the nervous system. However, restoring …

The increasing prevalence of neurological and psychiatric diseases, such as Alzheimer
disease and schizophrenia, necessitates the development of new research tools to …

The field of bioelectronics with the aim to contact cells, cell clusters, biological tissues and
organoids has become a vast enterprise. Currently, it is mainly relying on classical micro …

The regulation of most physiological processes relies on a state of equilibrium called
homeostasis, which is achieved through a biological control loop involving sensors and …

Studies have provided evidence that human cerebral organoids (hCOs) recapitulate
fundamental milestones of early brain development, but many important questions regarding …

Recent advances in the field of cellular reprogramming have opened a route to studying the
fundamental mechanisms underlying common neurological disorders. High‐density …

The electrophysiological technology having a high spatiotemporal resolution at the single‐
cell level and noninvasive measurements of large areas provide insights on underlying …

In bottom-up neuroscience, questions on neural information processing are addressed by
engineering small but reproducible biological neural networks of defined network topology …

Pharmaceutical compounds may have cardiotoxic properties, triggering potentially life-
threatening arrhythmias. To investigate proarrhythmic effects of drugs, the patch clamp …

Bottom-up neuroscience utilizes small, engineered biological neural networks to study
neuronal activity in systems of reduced complexity. We present a platform that establishes …