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Malaria: biology and disease
Malaria has been a major global health problem of humans through history and is a leading
cause of death and disease across many tropical and subtropical countries. Over the last …
cause of death and disease across many tropical and subtropical countries. Over the last …
Gliding motility powers invasion and egress in Apicomplexa
K Frénal, JF Dubremetz, M Lebrun… - Nature Reviews …, 2017 - nature.com
Protozoan parasites have developed elaborate motility systems that facilitate infection and
dissemination. For example, amoebae use actin-rich membrane extensions called …
dissemination. For example, amoebae use actin-rich membrane extensions called …
Atlas of Plasmodium falciparum intraerythrocytic development using expansion microscopy
Apicomplexan parasites exhibit tremendous diversity in much of their fundamental cell
biology, but study of these organisms using light microscopy is often hindered by their small …
biology, but study of these organisms using light microscopy is often hindered by their small …
Merozoite surface proteins in red blood cell invasion, immunity and vaccines against malaria
Malaria accounts for an enormous burden of disease globally, with Plasmodium falciparum
accounting for the majority of malaria, and P. vivax being a second important cause …
accounting for the majority of malaria, and P. vivax being a second important cause …
Malaria biology and disease pathogenesis: insights for new treatments
LH Miller, HC Ackerman, X Su, TE Wellems - Nature medicine, 2013 - nature.com
Plasmodium falciparum malaria, an infectious disease caused by a parasitic protozoan,
claims the lives of nearly a million children each year in Africa alone and is a top public …
claims the lives of nearly a million children each year in Africa alone and is a top public …
PCRCR complex is essential for invasion of human erythrocytes by Plasmodium falciparum
SW Scally, T Triglia, C Evelyn, BA Seager… - Nature …, 2022 - nature.com
The most severe form of malaria is caused by Plasmodium falciparum. These parasites
invade human erythrocytes, and an essential step in this process involves the ligand PfRh5 …
invade human erythrocytes, and an essential step in this process involves the ligand PfRh5 …
Revealing the Sequence and Resulting Cellular Morphology of Receptor-Ligand Interactions during Plasmodium falciparum Invasion of Erythrocytes
GE Weiss, PR Gilson, T Taechalertpaisarn… - PLoS …, 2015 - journals.plos.org
During blood stage Plasmodium falciparum infection, merozoites invade uninfected
erythrocytes via a complex, multistep process involving a series of distinct receptor-ligand …
erythrocytes via a complex, multistep process involving a series of distinct receptor-ligand …
The molecular basis of erythrocyte invasion by malaria parasites
Plasmodium species cause malaria by proliferating in human erythrocytes. Invasion of
immunologically privileged erythrocytes provides a relatively protective niche as well as …
immunologically privileged erythrocytes provides a relatively protective niche as well as …
The cellular and molecular basis for malaria parasite invasion of the human red blood cell
Malaria is a major disease of humans caused by protozoan parasites from the genus
Plasmodium. It has a complex life cycle; however, asexual parasite infection within the blood …
Plasmodium. It has a complex life cycle; however, asexual parasite infection within the blood …
Essential role of the PfRh5/PfRipr/CyRPA complex during Plasmodium falciparum invasion of erythrocytes
JC Volz, A Yap, X Sisquella, JK Thompson, NTY Lim… - Cell host & …, 2016 - cell.com
Plasmodium falciparum parasites in the merozoite stage invade human erythrocytes and
cause malaria. Invasion requires multiple interactions between merozoite ligands and …
cause malaria. Invasion requires multiple interactions between merozoite ligands and …