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Protein-based biological materials: Molecular design and artificial production
Polymeric materials produced from fossil fuels have been intimately linked to the
development of industrial activities in the 20th century and, consequently, to the …
development of industrial activities in the 20th century and, consequently, to the …
Synthetic extracellular matrices with function-encoding peptides
The communication of cells with their surroundings is mostly encoded in the epitopes of
structural and signalling proteins present in the extracellular matrix (ECM). These peptide …
structural and signalling proteins present in the extracellular matrix (ECM). These peptide …
Bioengineered 3D models of human pancreatic cancer recapitulate in vivo tumour biology
Patient-derived in vivo models of human cancer have become a reality, yet their turnaround
time is inadequate for clinical applications. Therefore, tailored ex vivo models that faithfully …
time is inadequate for clinical applications. Therefore, tailored ex vivo models that faithfully …
[HTML][HTML] Biofabrication methods for reconstructing extracellular matrix mimetics
In the human body, almost all cells interact with extracellular matrices (ECMs), which have
tissue and organ-specific compositions and architectures. These ECMs not only function as …
tissue and organ-specific compositions and architectures. These ECMs not only function as …
Resilin-mimetics as a smart biomaterial platform for biomedical applications
Intrinsically disordered proteins have dramatically changed the structure–function paradigm
of proteins in the 21st century. Resilin is a native elastic insect protein, which features …
of proteins in the 21st century. Resilin is a native elastic insect protein, which features …
In Situ Covalent Reinforcement of a Benzene‐1, 3, 5‐Tricarboxamide Supramolecular Polymer Enables Biomimetic, Tough, and Fibrous Hydrogels and Bioinks
Synthetic hydrogels often lack the load‐bearing capacity and mechanical properties of
native biopolymers found in tissue, such as cartilage. In natural tissues, toughness is often …
native biopolymers found in tissue, such as cartilage. In natural tissues, toughness is often …
Recent advances in the fabrication, functionalization, and bioapplications of peptide hydrogels
Self-assembled peptide-based nanomaterials have exhibited wide application potential in
the fields of materials science, nanodevices, biomedicine, tissue engineering, biosensors …
the fields of materials science, nanodevices, biomedicine, tissue engineering, biosensors …
Rational design of hydrogels for immunomodulation
The immune system protects organisms against endogenous and exogenous harm and
plays a key role in tissue development, repair and regeneration. Traditional …
plays a key role in tissue development, repair and regeneration. Traditional …
Biomaterials via peptide assembly: Design, characterization, and application in tissue engineering
A core challenge in biomaterials, with both fundamental significance and technological
relevance, concerns the rational design of bioactive microenvironments. Designed properly …
relevance, concerns the rational design of bioactive microenvironments. Designed properly …
Designed protein-and peptide-based hydrogels for biomedical sciences
Proteins are fundamentally the most important macromolecules for biochemical, mechanical,
and structural functions in living organisms. Therefore, they provide us with diverse structural …
and structural functions in living organisms. Therefore, they provide us with diverse structural …