Lansoprazole-induced osteoporosis via the IP3R-and SOCE-mediated calcium signaling pathways

Z Cheng, Y Liu, M Ma, S Sun, Z Ma, Y Wang, L Yu… - Molecular …, 2022 - Springer
Background Many clinical studies have shown a correlation between proton pump inhibitors
(PPIs) and osteoporosis or fractures. The purpose of this study was to establish a murine …

Naturally occurring organosulfur for treating metabolic disorders and infectious diseases

G Kumar - Medicinal Chemistry Research, 2024 - Springer
Sulfur has been used as a medicinal agent by the Greeks since ancient times.
Approximately 350 sulfur-containing compounds have been approved as drugs by the Food …

Neonatal gastroesophageal reflux

C Sawyer, R Sanghavi, EB Ortigoza - Early human development, 2022 - Elsevier
Gastroesophageal reflux disease (GERD) is a common diagnosis among neonates,
affecting 1 in 10 infants admitted to the neonatal intensive care unit. The diagnosis is …

Pantoprazole decreases gastroesophageal muscle tone in newborn rats via rho-kinase inhibition

C Welsh, MY Kasirer, J Pan… - American Journal of …, 2014 - journals.physiology.org
Proton pump inhibitors reduce gastric acid secretion and are commonly utilized in the
management of gastroesophageal reflux disease across all ages. Yet a decrease in lower …

[HTML][HTML] Clinical Use of Lansoprazole and the Risk of Osteoporosis: A Nationwide Cohort Study

MH Chung, YC Chen, WT Wu, MH Lin, YJ Yang… - International Journal of …, 2022 - mdpi.com
Background: Proton pump inhibitor (PPI) lansoprazole acts as a liver X receptor agonist,
which plays a crucial role in the crosstalk of osteoblasts and osteoclasts in vitro and during …

In vitro effects of rabeprazole on human pylorus tone

NF Yaşar, E Polat, M Duman… - Journal of …, 2015 - pmc.ncbi.nlm.nih.gov
Background/Aims It has been reported that proton pump inhibitors induce relaxation in
different types of smooth muscles. The aim of this study is to investigate in vitro effects of …

The effect of rabeprazole on LES tone in experimental rat model

M Duman, E Polat, M Ozer, Y Demirci… - Journal of …, 2013 - Taylor & Francis
Introduction: Despite adequate treatment with proton pump inhibitors (PPIs), symptoms of
gastroesophageal reflux disease (GERD) may remain persistent as well as Barrett's …

[PDF][PDF] 难治性胃食管反流病: 一个值得商榷的病名

黄雪, 白兴华 - **中西医结合消化杂志, 2018 - whuhzzs.com
严格来讲, 难治性胃食管反流病(refractory gastroesophagealrefluxdisease, rGERD)
不是独立的疾病名称, 而是贴在一部分经已有治疗手段无效的, 被认为是胃食管反流病(GERD) …

Proton Pompa Inhibitörü Ilaçlarin Umbilikal Arter Üzerine Etkileri

ET Öz - 2022 - search.proquest.com
TC NECMETTİN ERBAKAN ÜNİVERSİTESİ SAĞLIK BİLİMLERİ ENSTİTÜSÜ Tıbbi Farmakoloji
Anabilim Dalı PROTON POMPA İNHİ Page 1 i TC NECMETTİN ERBAKAN ÜNİVERSİTESİ …

Inhibition of Effects of Acetylcholine at Neuromuscular Junction by Omeprazole

A Azeem, A Khokhar, S Mumal, A Bashir… - Pakistan Journal of …, 2022 - pjmhsonline.com
Methods: In this experimental study both a student's oscillograph and a cumulative dosage
response curve were used to record the frog's rectus abdominis muscle contracting in …