Mechanical properties of cell sheets and spheroids: the link between single cells and complex tissues

YM Efremov, IM Zurina, VS Presniakova… - Biophysical …, 2021 - Springer
Cell aggregates, including sheets and spheroids, represent a simple yet powerful model
system to study both biochemical and biophysical intercellular interactions. However, it is …

Glaucoma and biomechanics

BN Safa, CA Wong, J Ha, CR Ethier - Current opinion in …, 2022 - journals.lww.com
Biomechanics remains an active aspect of glaucoma research, with activity in both basic
science and clinical translation. However, the role of biomechanics in glaucoma remains …

Wave-based optical coherence elastography: the 10-year perspective

F Zvietcovich, KV Larin - Progress in Biomedical Engineering, 2022 - iopscience.iop.org
After ten years of progress and innovation, optical coherence elastography (OCE) based on
the propagation of mechanical waves has become one of the major and the most studied …

Bayesian-neural-network-based strain estimation approach for optical coherence elastography

Y Bai, K Zhang, R Mo, Z Ni, Z He, S **e, B Dong - Optica, 2024 - opg.optica.org
Strain estimation is critical for quantitative elastography in quasi-static phase-sensitive
optical coherence elastography (PhS-OCE). Deep-learning methods have achieved …

[HTML][HTML] Geophysics-Inspired Nonlinear Stress–Strain Law for Biological Tissues and Its Applications in Compression Optical Coherence Elastography

VY Zaitsev, LA Matveev, AL Matveyev, AA Plekhanov… - Materials, 2024 - mdpi.com
We propose a nonlinear stress–strain law to describe nonlinear elastic properties of
biological tissues using an analogy with the derivation of nonlinear constitutive laws for …

Towards targeted colorectal cancer biopsy based on tissue morphology assessment by compression optical coherence elastography

AA Plekhanov, MA Sirotkina, EV Gubarkova… - Frontiers in …, 2023 - frontiersin.org
Identifying the precise topography of cancer for targeted biopsy in colonoscopic examination
is a challenge in current diagnostic practice. For the first time we demonstrate the use of …

Nonlinear elasticity assessment with optical coherence elastography for high-selectivity differentiation of breast cancer tissues

EV Gubarkova, AA Sovetsky, LA Matveev, AL Matveyev… - Materials, 2022 - mdpi.com
Soft biological tissues, breast cancer tissues in particular, often manifest pronounced
nonlinear elasticity, ie, strong dependence of their Young's modulus on the applied stress …

[HTML][HTML] Tumor spheroid elasticity estimation using mechano-microscopy combined with a conditional generative adversarial network

KY Foo, B Shaddy, J Murgoitio-Esandi… - Computer Methods and …, 2024 - Elsevier
Abstract Background and Objectives Techniques for imaging the mechanical properties of
cells are needed to study how cell mechanics influence cell function and disease …

Differentiation of breast tissue types for surgical margin assessment using machine learning and polarization-sensitive optical coherence tomography

D Zhu, J Wang, M Marjanovic, EJ Chaney… - Biomedical optics …, 2021 - opg.optica.org
We report an automated differentiation model for classifying malignant tumor, fibro-adipose,
and stroma in human breast tissues based on polarization-sensitive optical coherence …

Diagnostic accuracy of cross-polarization OCT and OCT-elastography for differentiation of breast cancer subtypes: comparative study

EV Gubarkova, EB Kiseleva, MA Sirotkina… - Diagnostics, 2020 - mdpi.com
The possibility to assess molecular-biological and morphological features of particular
breast cancer types can improve the precision of resection margin detection and enable …