Lung cancer cells and their sensitivity/resistance to cisplatin chemotherapy: Role of microRNAs and upstream mediators

M Ashrafizadeh, A Zarrabi, K Hushmandi, F Hashemi… - Cellular signalling, 2021 - Elsevier
Cisplatin (CP) is a well-known chemotherapeutic agent with excellent clinical effects. The
anti-tumor activity of CP has been demonstrated in different cancers such as breast, cervical …

MiRNA-based therapies for lung cancer: Opportunities and challenges?

H Yang, Y Liu, L Chen, J Zhao, M Guo, X Zhao, Z Wen… - Biomolecules, 2023 - mdpi.com
Lung cancer is a commonly diagnosed cancer and the leading cause of cancer-related
deaths, posing a serious health risk. Despite new advances in immune checkpoint and …

MicroRNAs and autoimmune-mediated eye diseases

Y Wei, N Li, L Zhao, C Yang, B Ma, X Li… - Frontiers in Cell and …, 2020 - frontiersin.org
MicroRNAs (miRNAs) are evolutionarily conserved short non-coding RNAs that act at post-
transcriptional regulation of gene expression by destroying target messenger RNA or …

A review on applications of abatacept in systemic rheumatic diseases

M Liu, Y Yu, S Hu - International Immunopharmacology, 2021 - Elsevier
Abatacept is a CTLA-4Ig fusion protein that selectively modulates the CD80/CD86: CD28
costimulatory pathway required for full T-cell activation. The FDA has approved it to be used …

MicroRNAs as regulators of immune checkpoints in cancer immunotherapy: targeting PD-1/PD-L1 and CTLA-4 pathways

A Zabeti Touchaei, S Vahidi - Cancer Cell International, 2024 - Springer
Immunotherapy has revolutionized cancer treatment by harnessing the power of the immune
system to eliminate tumors. Immune checkpoint inhibitors (ICIs) block negative regulatory …

Immunomodulatory role for MicroRNAs: Regulation of PD-1/PD-L1 and CTLA-4 immune checkpoints expression

N Skafi, M Fayyad-Kazan, B Badran - Gene, 2020 - Elsevier
The development and progression of different pathologies including, cancer, are associated
with suppressed immune responses. This restrained immune activity could be associated …

[HTML][HTML] The dual role of mir-146a in metastasis and disease progression

A Shahriar, GG Shiva, B Ghader, J Farhad… - Biomedicine & …, 2020 - Elsevier
Objective MicroRNAs are ribonucleic acids that are single-stranded and endogenous non-
coding acids that regulate gene expression in later stages of the translation process by …

[HTML][HTML] The role of microRNAs in COVID-19 with a focus on miR-200c

H Sodagar, S Alipour, S Hassani… - Journal of Circulating …, 2022 - ncbi.nlm.nih.gov
Objective: Epigenetics is a quickly spreading scientific field, and the study of epigenetic
regulation in various diseases such as infectious diseases is emerging. The …

Role of microRNA-146a in cancer development by regulating apoptosis

K Kookli, KT Soleimani, EF Amr, HM Ehymayed… - … -Research and Practice, 2024 - Elsevier
Despite great advances in diagnostic and treatment options for cancer, like chemotherapy
surgery, and radiation therapy it continues to remain a major global health concern. Further …

Role of non-coding RNAs and exosomal non-coding RNAs in vasculitis: A narrative review

X Tang, J Guo, F Qi, MJ Rezaei - International Journal of Biological …, 2024 - Elsevier
A category of very uncommon systemic inflammatory blood vessel illnesses known as
vasculitides. The pathogenesis and etiology of vasculitis are still poorly known. Despite all of …