The resistance mechanisms of bacteria against ciprofloxacin and new approaches for enhancing the efficacy of this antibiotic

A Shariati, M Arshadi, MA Khosrojerdi… - Frontiers in public …, 2022 - frontiersin.org
For around three decades, the fluoroquinolone (FQ) antibiotic ciprofloxacin has been used
to treat a range of diseases, including chronic otorrhea, endocarditis, lower respiratory tract …

Antimicrobial resistance

L Morrison, TR Zembower - Gastrointestinal Endoscopy …, 2020 - giendo.theclinics.com
Given recent media attention, it would be easy to assume that antimicrobial resistance is a
new problem; however, antimicrobial resistance has existed well before antimicrobials were …

Antibiotic resistance—the need for global solutions

R Laxminarayan, A Duse, C Wattal… - The Lancet infectious …, 2013 - thelancet.com
The causes of antibiotic resistance are complex and include human behaviour at many
levels of society; the consequences affect everybody in the world. Similarities with climate …

Mechanisms of quinolone action and resistance: where do we stand?

S Correia, P Poeta, M Hébraud… - Journal of medical …, 2017 - microbiologyresearch.org
Quinolone antibiotics represent one of the most important classes of anti-infective agents
and, although still clinically valuable, their use has been compromised by the increasing …

Escherichia coli in Europe: An Overview

N Allocati, M Masulli, MF Alexeyev, C Di Ilio - International journal of …, 2013 - mdpi.com
Escherichia coli remains one of the most frequent causes of several common bacterial
infections in humans and animals. E. coli is the prominent cause of enteritis, urinary tract …

Exploring variation of antibiotic resistance genes in activated sludge over a four-year period through a metagenomic approach

Y Yang, B Li, F Ju, T Zhang - Environmental science & technology, 2013 - ACS Publications
In this study, the profiles of ARGs in activated sludge from the Shatin WWTP of Hong Kong
were investigated using metagenomic analysis over a four-year period. Forty giga base …

A review of enrofloxacin for veterinary use

T Trouchon, S Lefebvre - Open Journal of Veterinary Medicine, 2016 - hal.science
This review outlines the current knowledge on the use of enrofloxacin in veterinary medicine
from biochemical mechanisms to the use in the field conditions and even resistance and …

Plasmid‐mediated quinolone resistance

GA Jacoby, J Strahilevitz… - Plasmids: Biology and …, 2015 - Wiley Online Library
Plasmid‐mediated quinolone resistance (PMQR) was late in being discovered. Nalidixic
acid, the first quinolone to be used clinically, was introduced in 1967 for urinary tract …

Enrofloxacin—the ruthless killer of eukaryotic cells or the last hope in the fight against bacterial infections?

Ł Grabowski, L Gaffke, K Pierzynowska… - International journal of …, 2022 - mdpi.com
Enrofloxacin is a compound that originates from a group of fluoroquinolones that is widely
used in veterinary medicine as an antibacterial agent (this antibiotic is not approved for use …

Transferable mechanisms of quinolone resistance from 1998 onward

J Ruiz - Clinical microbiology reviews, 2019 - Am Soc Microbiol
While the description of resistance to quinolones is almost as old as these antimicrobial
agents themselves, transferable mechanisms of quinolone resistance (TMQR) remained …