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[HTML][HTML] The Neurodegenerative Elderly Syndrome (NES) hypothesis: Alzheimer and Parkinson are two faces of the same disease
Increasing evidence suggests that Alzheimer's disease (AD) and Parkinson's disease (PD)
share monoamine and alpha-synuclein (αSyn) dysfunctions, often beginning years before …
share monoamine and alpha-synuclein (αSyn) dysfunctions, often beginning years before …
The Interplay of Mitochondrial Bioenergetics and Dopamine Agonists as an Effective Disease-Modifying Therapy for Parkinson's Disease
Neha, I Mazahir, SA Khan, P Kaushik, S Parvez - Molecular Neurobiology, 2024 - Springer
Parkinson's disease (PD) is a progressive neurological ailment with a slower rate of
advancement that is more common in older adults. The biggest risk factor for PD is getting …
advancement that is more common in older adults. The biggest risk factor for PD is getting …
Air Pollution and Parkinson Disease in a Population-Based Study
Importance The role of air pollution in risk and progression of Parkinson disease (PD) is
unclear. Objective To assess whether air pollution is associated with increased risk of PD …
unclear. Objective To assess whether air pollution is associated with increased risk of PD …
A dynamical model for the basal ganglia-thalamo-cortical oscillatory activity and its implications in Parkinson's disease
We propose to investigate brain electrophysiological alterations associated with Parkinson's
disease through a novel adaptive dynamical model of the network of the basal ganglia, the …
disease through a novel adaptive dynamical model of the network of the basal ganglia, the …
Perspective on investigation of neurodegenerative diseases with neurorobotics approaches
Neurorobotics has emerged from the alliance between neuroscience and robotics. It
pursues the investigation of reproducing living organism-like behaviors in robots by means …
pursues the investigation of reproducing living organism-like behaviors in robots by means …
[HTML][HTML] Unraveling sex differences in Parkinson's disease through explainable machine learning
Sex differences affect Parkinson's disease (PD) development and manifestation. Yet, current
PD identification and treatments underuse these distinctions. Sex-focused PD literature often …
PD identification and treatments underuse these distinctions. Sex-focused PD literature often …
[HTML][HTML] Multiple checkpoints of protein clearance machinery are modulated by a common microRNA, miR-4813-3p, through its putative target genes: Studies …
In order to maintain cellular homeostasis and a healthy state, aberrant and aggregated
proteins are to be recognized and rapidly cleared from cells. Parkinson's disease, known to …
proteins are to be recognized and rapidly cleared from cells. Parkinson's disease, known to …
Increasing serotonin to reduce parkinsonian tremor
While current dopamine-based drugs seem to be effective for most Parkinson's disease (PD)
motor dysfunctions, they produce variable responsiveness for resting tremor. This lack of …
motor dysfunctions, they produce variable responsiveness for resting tremor. This lack of …
Neurorobotic models of neurological disorders: a mini review
Modeling is widely used in biomedical research to gain insights into pathophysiology and
treatment of neurological disorders but existing models, such as animal models and …
treatment of neurological disorders but existing models, such as animal models and …
A biologically constrained spiking neural network model of the primate basal ganglia with overlap** pathways exhibits action selection
Action selection has been hypothesized to be a key function of the basal ganglia, yet the
nuclei involved, their interactions and the importance of the direct/indirect pathway …
nuclei involved, their interactions and the importance of the direct/indirect pathway …